Interactor 1: VGFR2 (P35918)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase NYK) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: Kdr
Interactor 2: PLCG1 (Q62077)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.39 | 1.00 | 0.625 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11387210 |
Identification Methods | coimmunoprecipitation, pull down |
Interaction Type | association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1 |
Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016477 - cell migration GO:0045766 - positive regulation of angiogenesis |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024