HitPredict

Interactor 1: FMR1 (P35922)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1) (mFmr1p)
Gene: FMR1

Interactor 2: EDC4 (Q3UJB9)
Enhancer of mRNA-decapping protein 4
Gene: EDC4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28671696
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 614 Mm			1 1406
+	Hs
		843742 FXR1_HUMAN (1-334): 0: 596: 73.95		EDC4_HUMAN (1-1406): 0: 1313: 94.81
+	Mm
		1112741 FXR1_MOUSE (1-334): 0: 589: 73.65		EDC4_MOUSE (1-1406): 0: 1319: 100.00
+	Hs
		844113 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		EDC4_HUMAN (1-1406): 0: 1313: 94.81
+	Mm
		1112743 Q8BPK8_MOUSE (268-399): 9.61e-11: 65.9: 16.91		EDC4_MOUSE (1-1406): 0: 1319: 100.00
+	Mm
		729602 FMR1_MOUSE (1-614): 0: 1011: 100.00		MACF1_MOUSE (938-1339): 3.46e-59: 228: 13.59
+	Hs
		989194 FMR1_HUMAN (1-614): 0: 995: 93.99		MACF1_HUMAN (938-1339): 4.93e-63: 240: 13.83
+	Hs
		988959 FMR1_HUMAN (1-614): 0: 995: 93.99		MCAF1_HUMAN (568-924): 1.2e-10: 68.6: 13.90
+	Hs
		257605 FMR1_HUMAN (1-614): 0: 995: 93.99		ANR17_HUMAN (439-1038): 1.89e-10: 68.2: 10.39
+	Hs
		843809 FXR1_HUMAN (1-334): 0: 596: 73.95		RIN3_HUMAN (505-1126): 1.16e-48: 191: 12.09
+	Hs
		2862 A0A0F7KYT8_HUMAN (1-334): 0: 589: 73.95		RIN3_HUMAN (505-1126): 1.16e-48: 191: 12.09
+	Hs
		257587 FXR1_HUMAN (1-334): 0: 596: 73.95		ANR17_HUMAN (439-1038): 1.89e-10: 68.2: 10.39
+	Hs
		257588 FXR2_HUMAN (268-524): 2.3e-57: 206: 32.72		ANR17_HUMAN (439-1038): 1.89e-10: 68.2: 10.39