Protein: ESRP2
Epithelial splicing regulatory protein 2 (RNA-binding motif protein 35B) (RNA-binding protein 35B)

Gene: ESRP2
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q9H6T0

Gene Ontology (top 5):
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1358663

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

2

19

High-throughput

0.628

High

537917

HSP7C
Heat shock cognate 71 kDa protein

2

8

High-throughput

0.621

High

573673

ENPL
Endoplasmin

2

7

High-throughput

0.601

High

74606

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

20

High-throughput

0.536

High

158504

RFXK
DNA-binding protein RFXANK

1

7

High-throughput

0.536

High

211421

RFOX2
RNA binding protein fox-1 homolog 2

1

17

High-throughput

0.536

High

457703

TBB5
Tubulin beta chain

1

7

High-throughput

0.536

High

1091080

FOXF2
Forkhead box protein F2

1

6

High-throughput

0.536

High

1316632

CDK20
Cyclin-dependent kinase 20

1

9

High-throughput

0.536

High

1338726

ANKK1
Ankyrin repeat and protein kinase domain-containing protein 1

1

4

High-throughput

0.536

High

1350327

MK15
Mitogen-activated protein kinase 15

1

7

High-throughput

0.536

High

1393911

HES6
Transcription cofactor HES-6

1

1

High-throughput

0.536

High

1406989

NPAS1
Neuronal PAS domain-containing protein 1

1

2

High-throughput

0.536

High

1420199

FOXP3
Forkhead box protein P3

1

6

High-throughput

0.536

High

1435156

MBNL1
Muscleblind-like protein 1

1

5

High-throughput

0.536

High

1435162

HSPB8
Heat shock protein beta-8

1

8

High-throughput

0.536

High

1037372

H11
Histone H1.1

1

18

High-throughput

0.515

High

261557

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

326161

REC8
Meiotic recombination protein REC8 homolog

1

0

High-throughput

0.513

High

1428326

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

347328

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.489

High

355108

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

1

High-throughput

0.489

High

366439

FA12
Coagulation factor XII

1

3

High-throughput

0.489

High

597015

TSHR
Thyrotropin receptor

1

4

High-throughput

0.489

High

841585

I12R1
Interleukin-12 receptor subunit beta-1

1

6

High-throughput

0.489

High

996854

TBA1B
Tubulin alpha-1B chain

1

3

High-throughput

0.489

High

1151876

RHOH
Rho-related GTP-binding protein RhoH

1

11

High-throughput

0.489

High

1177088

INF2
Inverted formin-2

1

1

High-throughput

0.489

High

1242366

PLBL1
Phospholipase B-like 1

1

1

High-throughput

0.489

High

1325839

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

1435159

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

1

High-throughput

0.489

High

1435163

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

5

High-throughput

0.489

High

48073

RBM47
RNA-binding protein 47

1

17

High-throughput

0.479

High

143259

NFIB
Nuclear factor 1 B-type

1

16

High-throughput

0.479

High

589693

RFA2
Replication protein A 32 kDa subunit

1

11

High-throughput

0.479

High

688313

TTP
mRNA decay activator protein ZFP36

1

7

High-throughput

0.479

High

696512

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

713852

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

20

High-throughput

0.479

High

769184

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

1114308

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1122161

UBP2L
Ubiquitin-associated protein 2-like

1

10

High-throughput

0.479

High

1152637

ELAV1
ELAV-like protein 1

1

20

High-throughput

0.479

High

1252778

RN111
E3 ubiquitin-protein ligase Arkadia

1

4

Small-scale

0.479

High

1289307

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

4

High-throughput

0.479

High

1356323

SMAP2
Stromal membrane-associated protein 2

1

3

High-throughput

0.479

High

1369840

CELF1
CUGBP Elav-like family member 1

1

20

High-throughput

0.479

High

1411710

RIOK1
Serine/threonine-protein kinase RIO1

1

11

High-throughput

0.479

High

1435155

BRD7
Bromodomain-containing protein 7

1

11

High-throughput

0.479

High

1435157

RNC
Ribonuclease 3

1

10

High-throughput

0.479

High

1435160

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

13

High-throughput

0.479

High

1397429

CI072
Guanine nucleotide exchange factor C9orf72

1

9

Small-scale

0.445

High

1435165

NUMBL
Numb-like protein

1

1

High-throughput

0.439

High

942889

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

15

High-throughput

0.437

High

1220800

RN123
E3 ubiquitin-protein ligase RNF123

1

20

High-throughput

0.437

High

1433893

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

574119

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

1

3

High-throughput

0.407

High

1253660

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.407

High

1435158

S22AB
Solute carrier family 22 member 11

1

1

High-throughput

0.407

High

289818

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

296830

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.279

Low

334245

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.279

Low

690054

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

1325920

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1350889

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1431578

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.279

Low

1435154

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

0

High-throughput

0.279

Low

1435161

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.279

Low

1435164

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.279

Low

1399028

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

1070453

ZNFS1
Putative uncharacterized protein ZNF252P-AS1

1

0

High-throughput

0.232

Low

1234030

S35E4
Solute carrier family 35 member E4

1

0

High-throughput

0.232

Low

1332137

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025