Interactor 1: VGFR1 (P35969)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Embryonic receptor kinase 2) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase receptor FLT)
Gene: Flt1

Interactor 2: VEGFA (Q00731)
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]
Gene: VEGFA

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17051153
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDGF~ig, Ig_3~PDGF
Common GO terms GO:0001525 - angiogenesis
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001666 - response to hypoxia
GO:0002040 - sprouting angiogenesis
GO:0005615 - extracellular space
and 8 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1333
Mm

1 392
+ Hs
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+ Dm
+ Dm
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+ Mm
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+ Hs

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Last updated: 15 Jul 2024