Interactor 1: BTK (P35991)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase) (Kinase EMB)
Gene: BTK

Interactor 2: BTK (P35991)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase) (Kinase EMB)
Gene: BTK

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 11007757, 23977012
Identification Methods protein kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains BTK~BTK, BTK~PH, PH~PH, PH~PK_Tyr_Ser-Thr, PH~SH3_1, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0001780 - neutrophil homeostasis
GO:0001805 - positive regulation of type III hypersensitivity
GO:0001812 - positive regulation of type I hypersensitivity
GO:0001818 - negative regulation of cytokine production
GO:0002250 - adaptive immune response
and 42 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 659
Mm

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Last updated: 15 Jul 2024