Protein: 1433Z
14-3-3 protein zeta (14-3-3-like protein) (Protein Leonardo)

Gene: 1433Z, 14-3-3zeta
Organism: Drosophila melanogaster
Interactions: 105
UniProt ID: P29310

Gene Ontology (top 5):
GO:0001223 - transcription coactivator binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

709527

1433E
14-3-3 protein epsilon

4

18

Small-scale

0.891

High

709521

1433Z
14-3-3 protein zeta

3

20

Small-scale

0.849

High

541183

KRAF1
Raf homolog serine/threonine-protein kinase Raf

2

20

High-throughput

0.713

High

709535

YAP1
Transcriptional coactivator yorkie

5

20

Small-scale

0.706

High

709604

IRS1
Insulin receptor substrate 1

4

20

Small-scale

0.686

High

709546

SLOB
Slowpoke-binding protein

3

20

Small-scale

0.672

High

709549

SINAL
Probable E3 ubiquitin-protein ligase sinah

3

12

High-throughput

0.653

High

479708

INSR
Insulin-like receptor

1

20

High-throughput

0.618

High

709553

FOXO
Forkhead box protein O

2

20

High-throughput

0.611

High

709561

Q9VCC9
LD23779p

2

20

High-throughput

0.611

High

120277

M9PD17
Gigas, isoform B

2

20

High-throughput

0.584

High

709567

Q9VHP9
Centromeric protein-C, isoform A

2

1

Small-scale

0.584

High

709574

GOLP3
Golgi phosphoprotein 3 homolog sauron

2

0

Small-scale

0.571

High

476906

NDKA
Nucleoside diphosphate kinase

2

5

High-throughput

0.571

High

649004

ANX10
Annexin B10

2

7

High-throughput

0.571

High

709528

SLO
Calcium-activated potassium channel slowpoke

1

15

Small-scale

0.550

High

709576

EXOC2
Exocyst complex component 2

1

2

High-throughput

0.541

High

709525

FAS2
Fasciclin-2

1

8

High-throughput

0.536

High

709531

SEM1A
Semaphorin-1A

1

3

High-throughput

0.536

High

119561

M9PAY7
Pi3K21B, isoform C

2

20

High-throughput

0.533

High

57744

A1ZB77
Uncharacterized protein, isoform J

1

10

High-throughput

0.508

High

691896

CAND
Calpain-D

1

1

High-throughput

0.508

High

709522

CSW
Tyrosine-protein phosphatase corkscrew

1

3

High-throughput

0.508

High

709524

FTZF1
Nuclear hormone receptor FTZ-F1

1

8

High-throughput

0.508

High

709551

Q95TJ6
LP01469p

1

15

High-throughput

0.508

High

709555

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.508

High

709556

Q9V3M9
Tektin

1

20

High-throughput

0.508

High

709559

Q9VBX3
Vig2, isoform B

1

7

High-throughput

0.508

High

709583

Q9VTZ0
GH08269p

1

3

High-throughput

0.508

High

709603

EXOC5
Exocyst complex component 5

1

1

High-throughput

0.494

High

709557

Q9V3T8
LD32469p

1

20

High-throughput

0.494

High

709533

STX1A
Syntaxin-1A

1

0

High-throughput

0.486

High

709534

PHYL
Protein phyllopod

1

0

High-throughput

0.486

High

709548

Q8SY02
Solute carrier organic anion transporter family member

1

0

High-throughput

0.486

High

709584

VERR
Protein verrocchio

1

0

High-throughput

0.486

High

709586

Q9VUR1
General transcription factor IIH subunit 4

1

0

High-throughput

0.486

High

709602

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.486

High

709536

Q59E49
Histone deacetylase

1

20

High-throughput

0.481

High

709543

Q7KTD2
SR family splicing factor SC35, isoform A

1

1

High-throughput

0.481

High

709544

Q7KUB0
Isocitrate dehydrogenase [NADP]

1

2

High-throughput

0.481

High

56258

A1ZA18
Kinesin heavy chain 73, isoform A

1

20

Small-scale

0.479

High

381694

H3
Histone H3

1

5

Small-scale

0.479

High

583658

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

11

Small-scale

0.479

High

709523

DLG1
Disks large 1 tumor suppressor protein

1

12

Small-scale

0.479

High

709529

GRAP
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

709530

SIMA
Protein similar

1

3

High-throughput

0.479

High

709532

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

20

High-throughput

0.479

High

709539

Q7K3H0
LD28067p

1

20

Small-scale

0.479

High

709541

Q7KMQ6
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

20

High-throughput

0.479

High

709542

Q7KNQ9
Connector enhancer of KSR protein CNK

1

20

High-throughput

0.479

High

709550

Q94533
Ribosomal protein S6 kinase

1

20

High-throughput

0.479

High

709552

Q95TN8
Serine/threonine-protein kinase greatwall

1

20

Small-scale

0.479

High

709560

CRERF
Protein CREBRF homolog

1

1

Small-scale

0.479

High

709565

TCTP
Translationally-controlled tumor protein homolog

1

3

Small-scale

0.479

High

709569

Q9VJX3
B4, isoform A

1

1

High-throughput

0.479

High

709573

RHEB
GTP-binding protein Rheb homolog

1

8

Small-scale

0.479

High

709585

PYRG
CTP synthase

1

5

High-throughput

0.479

High

709593

TNG2
Transport and Golgi organization protein 2

1

1

High-throughput

0.479

High

709597

DOS
Protein daughter of sevenless

1

20

High-throughput

0.479

High

709572

MON2
Protein MON2 homolog

1

8

High-throughput

0.464

High

709582

Q9VT19
RRM domain-containing protein

1

13

High-throughput

0.464

High

709588

Q9VVG2
Proline-rich extensin-like protein EPR1

1

20

High-throughput

0.464

High

709600

Q9W2S2
Autophagy-related 8a, isoform A

1

11

High-throughput

0.464

High

669578

OSKA
Maternal effect protein oskar

1

0

Small-scale

0.458

High

709554

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

709571

BOREA
Borealin

1

0

High-throughput

0.458

High

709577

ELP3
Elongator complex protein 3

1

0

Small-scale

0.458

High

709579

MELT
Protein melted

1

0

High-throughput

0.458

High

648857

ANXB9
Annexin B9

1

7

High-throughput

0.457

High

709581

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

2

High-throughput

0.457

High

709591

Q9VX75
Bazooka, isoform A

1

20

Small-scale

0.457

High

709594

Q9VYF3
Histone deacetylase

1

20

High-throughput

0.457

High

195002

O16043
Anon1A4

1

1

High-throughput

0.445

High

709526

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

5

High-throughput

0.445

High

709538

Q76NR6
Regucalcin

1

3

High-throughput

0.445

High

709566

JHD1
JmjC domain-containing histone demethylation protein 1

1

6

High-throughput

0.445

High

709587

Q9VV77
Polycomb group RING finger protein 3

1

20

High-throughput

0.445

High

709589

Q9VW83
Gigas, isoform A

1

20

High-throughput

0.445

High

58157

A1ZBG4
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

709537

Q6NNB4
Javelin-like, isoform C

1

1

High-throughput

0.439

High

709545

Q8IMH4
Saposin-related, isoform B

1

1

High-throughput

0.439

High

709568

NESD
Protein nessun dorma

1

8

Small-scale

0.437

High

709590

Q9VWJ6
FI03615p

1

8

High-throughput

0.437

High

709595

Q9VYR1
Regucalcin

1

3

High-throughput

0.437

High

709596

Q9VYT3
FI23714p1

1

4

Small-scale

0.437

High

58209

A1ZBG6
Uncharacterized protein, isoform C

1

1

High-throughput

0.417

High

95578

E2QDA1
FI15228p1

1

1

High-throughput

0.417

High

709564

Q9VFG3
Javelin-like, isoform A

1

1

High-throughput

0.417

High

709605

Q9Y125
BcDNA.GH08312

1

1

High-throughput

0.417

High

709540

Q7K9Q9
PAR-1 ser/thr kinase N2

1

1

High-throughput

0.381

High

709580

TO6BL
Meiotic recombination protein P22

3

0

High-throughput

0.340

High

471471

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.265

Low

709547

RNK
Ribonuclease kappa

1

0

High-throughput

0.265

Low

709562

Q9VCS1
IP04268p

1

0

High-throughput

0.265

Low

709563

Q9VDJ8
Cuticular protein 92F

1

0

High-throughput

0.265

Low

709570

Q9VKK3
AT28382p

1

0

High-throughput

0.265

Low

709575

Q9VQM2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

High-throughput

0.265

Low

709592

Q9VXP3
GH05406p

1

0

High-throughput

0.265

Low

709598

Q9W0H1
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

709599

PEB3
Ejaculatory bulb-specific protein 3

1

0

High-throughput

0.265

Low

709601

Q9W2W1
Uncharacterized protein, isoform A

1

0

High-throughput

0.251

Low

709558

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

Small-scale

0.249

Low

709578

Q9VRB7
GH11587p

1

0

High-throughput

0.238

Low

709606

R4I077
FI17832p1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025