HitPredict

Interactor 1: BTK (P35991)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase) (Kinase EMB)
Gene: BTK

Interactor 2: TBA1A (P68369)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Alpha-tubulin isotype M-alpha-1) (Tubulin alpha-1 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: Tuba1a

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0045121 - membrane raft GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 659 Mm			1 451
+	Hs
		933412 BTK_HUMAN (1-659): 0: 772: 98.33		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		933767 BTK_HUMAN (1-659): 0: 772: 98.33		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		522895 SRC_HUMAN (164-653): 7.99e-180: 523: 34.60		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		522894 SRC_HUMAN (164-653): 7.99e-180: 523: 34.60		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		427991 SRC_HUMAN (164-653): 7.99e-180: 523: 34.60		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		433849 LYN_HUMAN (154-653): 2.2e-166: 487: 34.52		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		411549 LCK_HUMAN (164-653): 3.9e-171: 499: 34.73		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		411668 LCK_HUMAN (164-653): 3.9e-171: 499: 34.73		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		782771 CSK_HUMAN (214-658): 1.4e-156: 460: 35.46		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428098 BLK_HUMAN (160-653): 1.26e-158: 467: 35.94		TBB5_HUMAN (1-439): 0: 695: 40.77