HitPredict

Interactor 1: PRS7 (P35998)
26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)
Gene: PSMC2

Interactor 2: ECM29 (Q5VYK3)
Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog)
Gene: ECPAS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	37071682, 35271311, 20682791
Identification Methods	cross-linking study, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 433 Hs			1 1845
+	Hs
		798694 PRS6B_HUMAN (3-425): 2.12e-121: 361: 35.93		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		907063 PRS8_HUMAN (35-430): 2.5e-119: 355: 45.20		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Hs
		913292 PRS10_HUMAN (39-429): 1.33e-119: 355: 42.46		ECM29_HUMAN (1-1845): 0: 1279: 100.00
+	Sc
		753435 PRS8_YEAST (16-417): 3.49e-154: 444: 44.53		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Sc
		703893 PRS7_YEAST (1-433): 1.68e-127: 378: 69.59		ECM29_YEAST (4-1740): 0: 678: 22.25
+	Rn
		956841 PRS7_RAT (1-433): 1.19e-143: 418: 99.77		CAND1_RAT (282-1301): 1.86e-34: 146: 12.77
+	Sc
		561052 PRS8_YEAST (16-417): 3.49e-154: 444: 44.53		EF3A_YEAST (1093-1349): 9.8e-14: 79.2: 17.11
+	Rn
		907220 PRS8_RAT (35-430): 2.5e-119: 355: 45.20		CAND1_RAT (282-1301): 1.86e-34: 146: 12.77