Protein: ARL8A
ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2)

Gene: ARL8A
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q96BM9

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1384766

ARL8B
ADP-ribosylation factor-like protein 8B

4

17

High-throughput

0.892

High

1367871

ARC1A
Actin-related protein 2/3 complex subunit 1A

1

6

High-throughput

0.691

High

1384767

SPG21
Maspardin

4

1

High-throughput

0.629

High

1270814

RUFY3
Protein RUFY3

1

8

High-throughput

0.618

High

1310002

PKHM2
Pleckstrin homology domain-containing family M member 2

1

7

High-throughput

0.618

High

1384757

RUFY1
RUN and FYVE domain-containing protein 1

1

9

High-throughput

0.618

High

1384764

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.618

High

418717

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

2

2

High-throughput

0.611

High

639398

5NTD
5'-nucleotidase

2

1

High-throughput

0.611

High

1384773

MYO6
Unconventional myosin-VI

2

5

High-throughput

0.611

High

1384752

MOCOS
Molybdenum cofactor sulfurase

3

3

High-throughput

0.607

High

1384765

RDH14
Retinol dehydrogenase 14

2

6

High-throughput

0.601

High

1211788

SYRM
Probable arginine--tRNA ligase, mitochondrial

2

1

High-throughput

0.558

High

177284

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

2

High-throughput

0.553

High

273568

DJC13
DnaJ homolog subfamily C member 13

1

6

High-throughput

0.536

High

488334

PPBI
Intestinal-type alkaline phosphatase

1

2

High-throughput

0.536

High

540615

LAMP1
Lysosome-associated membrane glycoprotein 1

1

14

High-throughput

0.536

High

691318

1433T
14-3-3 protein theta

1

12

High-throughput

0.536

High

730129

1433B
14-3-3 protein beta/alpha

1

12

High-throughput

0.536

High

774545

BASI
Basigin

1

7

High-throughput

0.536

High

845097

EAA3
Excitatory amino acid transporter 3

1

2

High-throughput

0.536

High

966719

1433G
14-3-3 protein gamma

1

12

High-throughput

0.536

High

971859

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

990586

1433Z
14-3-3 protein zeta/delta

1

12

High-throughput

0.536

High

1049649

1433F
14-3-3 protein eta

1

12

High-throughput

0.536

High

1115886

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.536

High

1120118

RB33A
Ras-related protein Rab-33A

1

18

High-throughput

0.536

High

1214355

SYT6
Synaptotagmin-6

1

4

High-throughput

0.536

High

1226415

TBC9B
TBC1 domain family member 9B

1

10

High-throughput

0.536

High

1270491

MARK2
Serine/threonine-protein kinase MARK2

1

5

High-throughput

0.536

High

1278207

CLAP1
CLIP-associating protein 1

1

1

High-throughput

0.536

High

1384755

VPS35
Vacuolar protein sorting-associated protein 35

1

2

High-throughput

0.536

High

1384763

GHITM
Growth hormone-inducible transmembrane protein

1

1

High-throughput

0.536

High

1384771

DDX41
Probable ATP-dependent RNA helicase DDX41

1

1

High-throughput

0.536

High

1384774

BAIP2
BAR/IMD domain-containing adapter protein 2

1

4

High-throughput

0.536

High

1384775

LAMP3
Lysosome-associated membrane glycoprotein 3

1

14

High-throughput

0.536

High

1384776

TPPC4
Trafficking protein particle complex subunit 4

1

2

High-throughput

0.536

High

1384779

KIF3A
Kinesin-like protein KIF3A

1

3

High-throughput

0.536

High

1384770

PUF60
Poly(U)-binding-splicing factor PUF60

1

5

High-throughput

0.523

High

260926

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.513

High

1187014

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.513

High

1384758

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

1

0

High-throughput

0.513

High

1384777

NTNG1
Netrin-G1

1

0

High-throughput

0.513

High

1384778

WASC3
WASH complex subunit 3

1

0

High-throughput

0.513

High

297068

DHRS3
Short-chain dehydrogenase/reductase 3

1

6

High-throughput

0.489

High

1254229

TBCD9
TBC1 domain family member 9

1

13

High-throughput

0.489

High

1357136

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.489

High

1384781

LIPG
Endothelial lipase

1

1

High-throughput

0.489

High

178358

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.479

High

178827

SCAM1
Secretory carrier-associated membrane protein 1

1

10

High-throughput

0.479

High

331218

KI20A
Kinesin-like protein KIF20A

1

13

High-throughput

0.479

High

404308

GCR
Glucocorticoid receptor

1

8

High-throughput

0.479

High

431869

ITB1
Integrin beta-1

1

3

High-throughput

0.479

High

474881

VIME
Vimentin

1

1

High-throughput

0.479

High

548577

MPRI
Cation-independent mannose-6-phosphate receptor

1

7

High-throughput

0.479

High

620512

NUCL
Nucleolin

1

3

High-throughput

0.479

High

1107091

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1108015

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

1155642

EZH2
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.479

High

1159798

OCLN
Occludin

1

5

High-throughput

0.479

High

1196294

GRAP1
GRIP1-associated protein 1

1

3

High-throughput

0.479

High

1229841

CYTSA
Cytospin-A

1

2

High-throughput

0.479

High

1233408

LTOR1
Ragulator complex protein LAMTOR1

1

7

High-throughput

0.479

High

1254974

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1275601

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

2

High-throughput

0.479

High

1280400

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.479

High

1314525

TM192
Transmembrane protein 192

1

1

High-throughput

0.479

High

1384761

SEM4C
Semaphorin-4C

1

1

High-throughput

0.479

High

1384772

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.479

High

1384783

COL10
Collectin-10

1

4

High-throughput

0.479

High

1135769

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1383772

TTC28
Tetratricopeptide repeat protein 28

1

0

High-throughput

0.458

High

1384753

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

184021

S22A1
Solute carrier family 22 member 1

1

2

High-throughput

0.445

High

530192

TAU
Microtubule-associated protein tau

1

12

High-throughput

0.445

High

934971

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.445

High

1119243

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

1273783

NIPA1
Magnesium transporter NIPA1

1

1

High-throughput

0.445

High

1384754

AURKB
Aurora kinase B

1

3

High-throughput

0.445

High

1384756

DIRC2
Solute carrier family 49 member 4

1

1

High-throughput

0.445

High

1384759

S12A9
Solute carrier family 12 member 9

1

11

High-throughput

0.445

High

1384760

TX101
Testis-expressed protein 101

1

2

High-throughput

0.445

High

49125

BLT3B
Bridge-like lipid transfer protein family member 3B

1

6

High-throughput

0.437

High

158581

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

2

High-throughput

0.437

High

883308

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

7

High-throughput

0.437

High

1229617

VIR
Protein virilizer homolog

1

2

High-throughput

0.437

High

1231277

BLT3A
Bridge-like lipid transfer protein family member 3A

1

6

High-throughput

0.437

High

1366977

ESR2
Estrogen receptor beta

1

8

High-throughput

0.437

High

1384762

SPRTN
DNA-dependent metalloprotease SPRTN

1

4

High-throughput

0.437

High

1384769

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.437

High

424536

PAI2
Plasminogen activator inhibitor 2

1

0

High-throughput

0.426

High

539622

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.426

High

999395

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.426

High

462796

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

3

0

High-throughput

0.352

High

1326683

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

1360339

ATRIP
ATR-interacting protein

1

0

High-throughput

0.279

Low

1384780

ZSC21
Zinc finger and SCAN domain-containing protein 21

1

0

High-throughput

0.279

Low

1384782

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.279

Low

377679

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

916018

NUP98
Nuclear pore complex protein Nup98-Nup96

1

0

High-throughput

0.249

Low

1250897

SOSD1
Sclerostin domain-containing protein 1

1

0

Small-scale

0.249

Low

1384768

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.249

Low

445671

KCRM
Creatine kinase M-type

1

0

High-throughput

0.232

Low

1358542

POF1B
Protein POF1B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025