HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	36931259, 37120454, 15778465
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0030307 - positive regulation of cell growth
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 1708
+	Hs
		971663 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		990370 1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		691142 1433T_HUMAN (1-238): 1e-107: 312: 71.85		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		729965 1433B_HUMAN (1-239): 3.42e-100: 293: 68.62		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		966486 1433G_HUMAN (1-242): 1.87e-98: 289: 65.16		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		1049440 1433F_HUMAN (2-242): 2.79e-96: 283: 64.20		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Dm
		1019949 1433E_DROME (2-247): 2.82e-144: 405: 58.07		Q9VWJ6_DROME (1566-1694): 2.65e-11: 71.3: 34.62
+	Dm
		709590 1433Z_DROME (1-245): 4.73e-99: 290: 66.12		Q9VWJ6_DROME (1566-1694): 2.65e-11: 71.3: 34.62