HitPredict

Interactor 1: VPS21 (P36017)
Vacuolar protein sorting-associated protein 21 (GTP-binding protein YPT51) (Vacuolar protein-targeting protein 12)
Gene: VPS21

Interactor 2: VPS9 (P54787)
Vacuolar protein sorting-associated protein 9 (Vacuolar protein-targeting protein 9)
Gene: VPS9

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.870

The method score is based on:

Property Details
Experiments 10329739, 31038239, 22157956
Identification Methods enzymatic study, two hybrid, protein complementation assay, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~VPS9
Common GO terms GO:0000011 - vacuole inheritance
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0006623 - protein targeting to vacuole
GO:0006895 - Golgi to endosome transport
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 210
Sc

1 451
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Dm
+ At
+ Dm
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024