Protein: GT2D1
General transcription factor II-I repeat domain-containing protein 1 (GTF2I repeat domain-containing protein 1) (General transcription factor III) (MusTRD1/BEN) (Muscle TFII-I repeat domain-containing protein 1) (Slow-muscle-fiber enhancer-binding protein) (USE B1-binding protein) (Williams-Beuren syndrome chromosomal region 11 protein) (Williams-Beuren syndrome chromosomal region 12 protein)

Gene: GT2D1, GTF2IRD1
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q9UHL9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508789

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

1

High-throughput

0.655

High

848833

MAGAA
Melanoma-associated antigen 10

3

3

High-throughput

0.650

High

1232059

GTD2B
General transcription factor II-I repeat domain-containing protein 2B

2

5

High-throughput

0.611

High

1460003

FBW1B
F-box/WD repeat-containing protein 11

2

2

High-throughput

0.611

High

1134567

NOLC1
Nucleolar and coiled-body phosphoprotein 1

2

0

High-throughput

0.602

High

1458816

ZMYM2
Zinc finger MYM-type protein 2

2

5

Small-scale

0.596

High

297878

PIAS2
E3 SUMO-protein ligase PIAS2

2

3

Small-scale

0.594

High

188382

HDAC3
Histone deacetylase 3

2

3

Small-scale

0.584

High

1118004

PKP1
Plakophilin-1

1

3

Small-scale

0.573

High

1202256

DCAF6
DDB1- and CUL4-associated factor 6

1

1

Small-scale

0.552

High

1250474

MCAF1
Activating transcription factor 7-interacting protein 1

1

0

Small-scale

0.549

High

1359993

MB3L1
Methyl-CpG-binding domain protein 3-like 1

1

0

Small-scale

0.549

High

1385764

INT12
Integrator complex subunit 12

1

0

Small-scale

0.549

High

127409

LEG8
Galectin-8

1

2

High-throughput

0.536

High

425669

ISG15
Ubiquitin-like protein ISG15

1

2

High-throughput

0.536

High

426967

FGF1
Fibroblast growth factor 1

1

1

High-throughput

0.536

High

856971

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.536

High

1120379

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

1

High-throughput

0.536

High

1244489

ULK3
Serine/threonine-protein kinase ULK3

1

1

High-throughput

0.536

High

1288861

GTD2A
General transcription factor II-I repeat domain-containing protein 2A

1

5

High-throughput

0.536

High

1369545

KIFA3
Kinesin-associated protein 3

1

5

High-throughput

0.536

High

1447655

ZC4H2
Zinc finger C4H2 domain-containing protein

1

0

Small-scale

0.529

High

1452119

ZN586
Zinc finger protein 586

1

2

High-throughput

0.515

High

250882

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

600242

ZNF23
Zinc finger protein 23

1

0

High-throughput

0.513

High

617752

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.513

High

1206922

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.513

High

1226748

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

0

High-throughput

0.513

High

1234762

SPOPL
Speckle-type POZ protein-like

1

0

High-throughput

0.513

High

1361176

PIBF1
Progesterone-induced-blocking factor 1

1

0

High-throughput

0.513

High

1402090

CRML
Protein cramped-like

1

0

High-throughput

0.513

High

1402983

ZN382
Zinc finger protein 382

1

0

High-throughput

0.513

High

1405066

SORT
Sortilin

1

0

High-throughput

0.513

High

297706

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

Small-scale

0.508

High

911148

IMA1
Importin subunit alpha-1

1

4

Small-scale

0.508

High

1408352

PKP2
Plakophilin-2

1

4

Small-scale

0.508

High

1460001

ZMYM5
Zinc finger MYM-type protein 5

1

5

Small-scale

0.508

High

1448736

ADPPT
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

1

0

High-throughput

0.493

High

1450871

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

0

High-throughput

0.493

High

472405

FGF4
Fibroblast growth factor 4

1

1

High-throughput

0.489

High

760510

SDC2
Syndecan-2

1

1

High-throughput

0.489

High

1389517

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

1

High-throughput

0.489

High

1350199

ALMS1
Centrosome-associated protein ALMS1

1

0

Small-scale

0.486

High

1446203

EXOS4
Exosome complex component RRP41

1

0

High-throughput

0.486

High

138782

IMA4
Importin subunit alpha-4

1

4

Small-scale

0.481

High

142632

IMA3
Importin subunit alpha-3

1

4

Small-scale

0.481

High

911424

IMA5
Importin subunit alpha-5

1

4

Small-scale

0.481

High

1460005

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

1

Small-scale

0.481

High

362396

ABL1
Tyrosine-protein kinase ABL1

1

1

High-throughput

0.479

High

474353

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

648385

USF1
Upstream stimulatory factor 1

1

3

Small-scale

0.479

High

799553

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

980499

H4
Histone H4

1

1

High-throughput

0.479

High

1088081

NFIA
Nuclear factor 1 A-type

1

2

High-throughput

0.479

High

1133719

NFIX
Nuclear factor 1 X-type

1

2

High-throughput

0.479

High

1153939

SMAD2
Mothers against decapentaplegic homolog 2

1

3

Small-scale

0.479

High

1418500

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.479

High

905258

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

1089050

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

464074

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

2

High-throughput

0.457

High

648717

FGFR4
Fibroblast growth factor receptor 4

1

2

High-throughput

0.437

High

1393549

MR1L1
MORF4 family-associated protein 1-like 1

2

0

High-throughput

0.316

High

1436714

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.316

High

378244

IFNA1
Interferon alpha-1/13

1

0

High-throughput

0.279

Low

709284

AA2BR
Adenosine receptor A2b

1

0

High-throughput

0.279

Low

1053167

STP2
Nuclear transition protein 2

1

0

High-throughput

0.279

Low

1093783

GAGE5
G antigen 5

1

0

High-throughput

0.279

Low

1211913

AKND1
Protein AKNAD1

1

0

High-throughput

0.279

Low

1395234

LRIQ1
Leucine-rich repeat- and IQ domain-containing protein 1

1

0

High-throughput

0.279

Low

1460002

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.279

Low

1460004

WASF3
Actin-binding protein WASF3

1

0

High-throughput

0.279

Low

1163823

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

0

High-throughput

0.269

Low

1226836

ATG9B
Autophagy-related protein 9B

1

0

High-throughput

0.269

Low

1352149

EOLA1
Protein EOLA1

1

0

High-throughput

0.269

Low

1430560

TM168
Transmembrane protein 168

1

0

High-throughput

0.269

Low

1446504

KRCC1
Lysine-rich coiled-coil protein 1

1

0

High-throughput

0.269

Low

184940

SPTC1
Serine palmitoyltransferase 1

1

0

Small-scale

0.251

Low

1013351

HTRA4
Serine protease HTRA4

1

0

Small-scale

0.251

Low

1023403

AT2C1
Calcium-transporting ATPase type 2C member 1

1

0

Small-scale

0.251

Low

1326577

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

Small-scale

0.251

Low

1410662

SELS
Selenoprotein S

1

0

Small-scale

0.251

Low

1226555

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025