HitPredict

Interactor 1: YPT52 (P36018)
GTP-binding protein YPT52
Gene: YPT52

Interactor 2: GYP3 (P48566)
GTPase-activating protein GYP3 (Multicopy suppressor of bud emergence 3) (Protein MSB3)
Gene: MSB3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	22593206
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0005770 - late endosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 234 Sc			1 633
+	Sc
		731185 VPS21_YEAST (5-232): 5.97e-57: 181: 48.25		GYP3_YEAST (1-633): 6.71e-180: 526: 100.00
+	Hs
		232698 RAB2B_HUMAN (4-233): 1.32e-72: 221: 28.87		TBCD4_HUMAN (23-601): 1.23e-87: 299: 14.95
+	Hs
		914176 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		TBCD1_HUMAN (23-596): 1.15e-83: 286: 14.31
+	Os
		772871 RIC2_ORYSJ (4-234): 3.03e-75: 228: 30.74		Q5SMT0_ORYSJ (27-507): 1.72e-84: 280: 16.37
+	Hs
		914482 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		RBGP1_HUMAN (31-629): 2.28e-83: 285: 16.92
+	Hs
		844684 RAB5C_HUMAN (3-234): 1.58e-79: 239: 46.55		SGSM3_HUMAN (138-571): 2.46e-79: 268: 24.37
+	Hs
		321281 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		TBCD8_HUMAN (35-555): 1.65e-81: 280: 20.76
+	Os
		1130874 Q7XHP7_ORYSJ (4-233): 6.49e-73: 222: 29.57		Q5SMT0_ORYSJ (27-507): 1.72e-84: 280: 16.37
+	Os
		1130875 Q84TA8_ORYSJ (4-233): 3.72e-72: 220: 29.57		Q5SMT0_ORYSJ (27-507): 1.72e-84: 280: 16.37
+	Hs
		234370 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		EVI5_HUMAN (145-552): 2.64e-81: 274: 19.57
+	Hs
		234378 RB11B_HUMAN (4-233): 8.23e-72: 219: 32.62		EVI5_HUMAN (145-552): 2.64e-81: 274: 19.57
+	Hs
		72915 RAB5C_HUMAN (3-234): 1.58e-79: 239: 46.55		B4DMS2_HUMAN (181-571): 1.18e-75: 254: 25.51
+	Hs
		914465 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		TBD2B_HUMAN (111-573): 5.72e-78: 268: 23.03
+	Hs
		914275 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		EVI5L_HUMAN (116-581): 1.48e-77: 264: 17.34
+	Hs
		1079952 RB11B_HUMAN (4-233): 8.23e-72: 219: 32.62		EVI5L_HUMAN (116-581): 1.48e-77: 264: 17.34
+	Hs
		914391 RB11A_HUMAN (4-233): 2.3e-73: 223: 33.33		TB22B_HUMAN (9-520): 1.34e-77: 257: 12.55
+	Hs
		592434 RAB5A_HUMAN (3-234): 3.63e-56: 179: 46.35		SGSM3_HUMAN (138-571): 2.46e-79: 268: 24.37
+	Hs
		592584 RAB5A_HUMAN (3-234): 3.63e-56: 179: 46.35		TBD2B_HUMAN (111-573): 5.72e-78: 268: 23.03
+	Hs
		895374 RAB5B_HUMAN (3-234): 1.64e-53: 173: 43.97		SGSM3_HUMAN (138-571): 2.46e-79: 268: 24.37
+	Hs
		592528 RAB5A_HUMAN (3-234): 3.63e-56: 179: 46.35		TB22B_HUMAN (9-520): 1.34e-77: 257: 12.55