HitPredict

Interactor 1: SN114 (P36048)
Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10)
Gene: SNU114

Interactor 2: LSM8 (P47093)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	1.00	0.887

Property	Details
Experiments	10747033, 23560879, 37968396, 16429126
Identification Methods	biochemical, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GTP_EFTU~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0005737 - cytoplasm GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1008 Sc			1 109
+	Hs
		321402 U5S1_HUMAN (2-1007): 0: 898: 31.43		LSM8_HUMAN (1-85): 1.33e-29: 103: 27.47
+	Sc
		731738 SN114_YEAST (1-1008): 0: 895: 100.00		LSM1_YEAST (2-108): 1.12e-29: 106: 20.18
+	Hs
		167690 U5S1_HUMAN (2-1007): 0: 898: 31.43		LSM1_HUMAN (2-102): 1.21e-28: 102: 21.70
+	Hs
		912044 U5S1_HUMAN (2-1007): 0: 898: 31.43		RUXG_HUMAN (3-69): 6.78e-25: 90.8: 20.29
+	Hs
		68421 U5S1_HUMAN (2-1007): 0: 898: 31.43		RUXGL_HUMAN (3-69): 6.48e-23: 85.8: 20.29
+	Hs
		1064819 U5S1_HUMAN (2-1007): 0: 898: 31.43		LSM7_HUMAN (5-81): 4.87e-19: 77: 17.24
+	Hs
		927954 U5S1_HUMAN (2-1007): 0: 898: 31.43		RSMN_HUMAN (2-64): 5.94e-17: 74.7: 20.00
+	Hs
		538964 U5S1_HUMAN (2-1007): 0: 898: 31.43		RSMB_HUMAN (2-64): 9.82e-17: 74.3: 20.00
+	Sc
		731731 SN114_YEAST (1-1008): 0: 895: 100.00		RUXG_YEAST (2-69): 1.63e-17: 72.4: 21.62
+	Sc
		731750 SN114_YEAST (1-1008): 0: 895: 100.00		LSM7_YEAST (5-71): 3.29e-13: 62.3: 15.00
+	Sc
		731753 SN114_YEAST (1-1008): 0: 895: 100.00		LSM3_YEAST (5-76): 5.4e-10: 53.5: 22.22
+	Sp
		252592 SN114_SCHPO (1-1007): 0: 841: 32.82		RUXG_SCHPO (2-69): 6.68e-18: 73.1: 17.14
+	Sp
		292950 SN114_SCHPO (1-1007): 0: 841: 32.82		RSMB_SCHPO (2-65): 3.19e-11: 58.1: 16.88
+	Zm
		5855 A0A1D6E4M0_MAIZE (131-958): 0: 560: 17.65		B4FMM6_MAIZE (3-68): 4.77e-22: 83.9: 22.39
+	Sc
		810526 RIA1_YEAST (117-482): 3.67e-102: 347: 22.01		LSM1_YEAST (2-108): 1.12e-29: 106: 20.18