HitPredict

Interactor 1: B4E1U9 (B4E1U9)
Cell division control protein 42 homolog (EC 3.6.5.2)
Gene: B4E1U9

Interactor 2: RIN3 (Q8TB24)
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
Gene: RIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32552912
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ras~VPS9
Common GO terms	GO:0006897 - endocytosis
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 985
+	Ce
		104435 RAC1_CAEEL (1-236): 2.11e-77: 233: 52.97		G5EBS9_CAEEL (477-958): 1.73e-56: 213: 20.04
+	Hs
		166043 RAC1_HUMAN (1-236): 8.61e-78: 234: 56.54		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Hs
		166039 RAC3_HUMAN (1-222): 9.47e-72: 219: 57.21		SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77
+	Hs
		892445 RAC3_HUMAN (1-222): 9.47e-72: 219: 57.21		RINL_HUMAN (520-874): 3.79e-39: 156: 24.32
+	Dm
		776893 RAC1_DROME (1-236): 1.88e-75: 228: 55.70		SPRI_DROME (34-706): 2.23e-33: 142: 16.72
+	Dm
		819744 RAC2_DROME (1-236): 1.27e-73: 223: 54.43		SPRI_DROME (34-706): 2.23e-33: 142: 16.72
+	Hs
		297840 RHOJ_HUMAN (2-233): 2.55e-78: 236: 51.72		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Hs
		297823 RAC1_HUMAN (1-236): 8.61e-78: 234: 56.54		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Ce
		105104 RAC1_CAEEL (1-236): 2.11e-77: 233: 52.97		G5ECF0_CAEEL (17-239): 1.52e-22: 106: 22.27
+	Hs
		297827 RHOG_HUMAN (1-236): 9.96e-76: 229: 48.73		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Hs
		297812 RAC2_HUMAN (1-236): 1.08e-73: 223: 54.85		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Hs
		297820 RHOA_HUMAN (5-236): 1.19e-72: 221: 42.67		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Hs
		297819 RAC3_HUMAN (1-222): 9.47e-72: 219: 57.21		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Hs
		297809 RHOC_HUMAN (5-236): 1.3e-70: 215: 41.81		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Hs
		297834 RHOU_HUMAN (4-231): 1.03e-64: 203: 47.41		K0754_HUMAN (6-390): 5.17e-23: 108: 12.47
+	Hs
		867087 CDC42_HUMAN (1-236): 8.11e-75: 226: 80.51		SC24C_HUMAN (104-426): 8.78e-10: 64.8: 11.28