Interactor 1: KAE1 (P36132)
tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (Kinase-associated endopeptidase 1) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein KAE1) (tRNA threonylcarbamoyladenosine biosynthesis protein KAE1)
Gene: KAE1

Interactor 2: BUD32 (P53323)
EKC/KEOPS complex subunit BUD32 (EC 3.6.-.-) (Atypical serine/threonine protein kinase BUD32) (EC 2.7.11.1) (Bud site selection protein 32) (Low-dye-binding protein 14) (piD261)
Gene: BUD32

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.759

The method score is based on:

Property Details
Experiments 11805837, 16564010, 18951093, 19172740, 14519092, 18467557, 37968396, 16874308, 16429126
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, far western blotting, pull down, two hybrid, protein complementation assay, enzymatic study, molecular sieving, tandem affinity purification, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000408 - EKC/KEOPS complex
GO:0000723 - telomere maintenance
GO:0000722 - telomere maintenance via recombination
GO:0002949 - tRNA threonylcarbamoyladenosine modification
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 386
Sc

1 261
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024