HitPredict

Interactor 1: TRI23 (P36406)
E3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Gene: TRIM23

Interactor 2: BAG1 (Q99933)
BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)
Gene: BAG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.840

Property	Details
Experiments	25416956, 19060904
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 574 Hs			1 345
+	Hs
		950550 ARF1_HUMAN (390-569): 5.89e-71: 227: 57.22		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Hs
		574739 ARF4_HUMAN (393-568): 1.47e-70: 226: 55.11		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Hs
		950690 ARF5_HUMAN (392-568): 1.63e-69: 223: 55.37		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00
+	Hs
		1307201 RAB1B_HUMAN (397-569): 7.05e-60: 199: 15.17		BAG1_HUMAN (1-345): 4.2e-176: 493: 100.00