HitPredict

Interactor 1: LONM (P36776)
Lon protease homolog, mitochondrial (EC 3.4.21.53) (LONHs) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)
Gene: LONP1

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 959 Hs			1 193
+	Hs
		737298 LONM_HUMAN (1-959): 0: 1123: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436180 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		737310 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		737288 LONM_HUMAN (1-959): 0: 1123: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545238 LONM_HUMAN (1-959): 0: 1123: 100.00		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		737287 LONM_HUMAN (1-959): 0: 1123: 100.00		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		737297 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120329 LONM_HUMAN (1-959): 0: 1123: 100.00		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		874762 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		874798 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436226 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		874753 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545289 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		874748 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		874786 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120367 TERA_HUMAN (107-762): 3.63e-149: 463: 14.23		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Sc
		580299 CDC48_YEAST (132-751): 9.63e-138: 434: 13.94		CDC42_YEAST (1-193): 2.09e-74: 223: 50.26
+	Sp
		963940 CDC48_SCHPO (132-748): 8.67e-136: 428: 12.69		CDC42_SCHPO (1-193): 2.66e-76: 228: 53.09
+	Hs
		925550 YMEL1_HUMAN (219-831): 3.25e-97: 325: 14.37		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22