HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: Q05BL1 (Q05BL1)
TP53BP2 protein
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 323 Hs			1 1048
+	Hs
		737795 PP1G_HUMAN (1-323): 0: 603: 100.00		ASPP2_HUMAN (7-1048): 1.52e-161: 508: 99.71
+	Hs
		905884 PP1A_HUMAN (1-323): 0: 579: 90.66		ASPP2_HUMAN (7-1048): 1.52e-161: 508: 99.71
+	Hs
		905849 PP1A_HUMAN (1-323): 0: 579: 90.66		Q05BL1_HUMAN (1-1048): 3.21e-158: 497: 100.00
+	Mm
		93784 PP1A_MOUSE (1-323): 0: 579: 90.36		E9QJU8_MOUSE (7-1048): 3.29e-150: 478: 89.93
+	Hs
		737981 PP1G_HUMAN (1-323): 0: 603: 100.00		ASPP1_HUMAN (10-1048): 1.44e-101: 346: 44.03
+	Mm
		906278 PP1A_MOUSE (1-323): 0: 579: 90.36		ASPP1_MOUSE (10-1048): 2.06e-103: 351: 43.08
+	Hs
		737941 PP1G_HUMAN (1-323): 0: 603: 100.00		IASPP_HUMAN (301-1047): 2.1e-53: 203: 21.33
+	Mm
		906260 PP1A_MOUSE (1-323): 0: 579: 90.36		IASPP_MOUSE (301-1047): 1.69e-56: 212: 20.89
+	Hs
		737978 PP1G_HUMAN (1-323): 0: 603: 100.00		PP16A_HUMAN (859-957): 8.99e-21: 99.5: 33.33
+	Hs
		737999 PP1G_HUMAN (1-323): 0: 603: 100.00		PP16B_HUMAN (865-957): 1.31e-19: 96.1: 36.56
+	Hs
		161322 PP1G_HUMAN (1-323): 0: 603: 100.00		MYPT1_HUMAN (877-979): 4.12e-16: 85.7: 36.89
+	Mm
		926555 PP1G_MOUSE (1-323): 0: 602: 99.69		MYPT1_MOUSE (811-979): 8.48e-16: 84.5: 26.74
+	Hs
		738024 PP1G_HUMAN (1-323): 0: 603: 100.00		PP12C_HUMAN (826-954): 9.69e-12: 71.4: 23.88
+	Hs
		225129 PP1G_HUMAN (1-323): 0: 603: 100.00		MYPT2_HUMAN (867-955): 1.87e-11: 70.7: 33.71
+	Hs
		161347 PP1A_HUMAN (1-323): 0: 579: 90.66		MYPT1_HUMAN (877-979): 4.12e-16: 85.7: 36.89
+	Mm
		906366 PP1A_MOUSE (1-323): 0: 579: 90.36		MYPT1_MOUSE (811-979): 8.48e-16: 84.5: 26.74
+	Hs
		905895 PP1A_HUMAN (1-323): 0: 579: 90.66		KANK1_HUMAN (905-1048): 1.14e-12: 74.5: 16.34
+	Mm
		906252 PP1A_MOUSE (1-323): 0: 579: 90.36		PP12C_MOUSE (826-956): 9.17e-13: 74.5: 24.27
+	Mm
		906293 PP1A_MOUSE (1-323): 0: 579: 90.36		MYPT2_MOUSE (867-955): 4.18e-12: 72.6: 33.71
+	Hs
		225132 PP1A_HUMAN (1-323): 0: 579: 90.66		MYPT2_HUMAN (867-955): 1.87e-11: 70.7: 33.71