Interactor 1: RPN12 (P32496)
26S proteasome regulatory subunit RPN12 (Nuclear integrity protein 1)
Gene: RPN12

Interactor 2: RPN8 (Q08723)
26S proteasome regulatory subunit RPN8
Gene: RPN8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 11595789, 11805826, 16554755, 16429126, 37968396, 31848235, 22195964, 22940862, 14759368
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN8_PSD8_EIF3K~MitMem_reg
Common GO terms GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 274
Sc

1 338
+ Hs
+ Dm
+ Sp
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025