HitPredict

Interactor 1: TNR3 (P36941)
Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III)
Gene: LTBR

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 435 Hs			1 193
+	Hs
		738654 TNR3_HUMAN (1-435): 8.16e-134: 393: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		584359 TNR1A_HUMAN (36-338): 1.98e-54: 189: 21.43		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		584368 TNR1A_HUMAN (36-338): 1.98e-54: 189: 21.43		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436154 TNR1A_HUMAN (36-338): 1.98e-54: 189: 21.43		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		154335 TR10B_HUMAN (24-356): 2.22e-43: 159: 18.66		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		154338 TR10B_HUMAN (24-356): 2.22e-43: 159: 18.66		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		267336 TNR21_HUMAN (50-229): 2.6e-42: 160: 26.11		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		154295 TR10B_HUMAN (24-356): 2.22e-43: 159: 18.66		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		154343 TR10B_HUMAN (24-356): 2.22e-43: 159: 18.66		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		154333 TR10B_HUMAN (24-356): 2.22e-43: 159: 18.66		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		154300 TR10B_HUMAN (24-356): 2.22e-43: 159: 18.66		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		267341 TNR21_HUMAN (50-229): 2.6e-42: 160: 26.11		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		154332 TR10B_HUMAN (24-356): 2.22e-43: 159: 18.66		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		154336 TR10B_HUMAN (24-356): 2.22e-43: 159: 18.66		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		632236 TNR6_HUMAN (13-169): 4.9e-34: 131: 26.63		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		121431 TR10A_HUMAN (30-173): 4.27e-24: 106: 28.77		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		121466 TR10A_HUMAN (30-173): 4.27e-24: 106: 28.77		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		121436 TR10A_HUMAN (30-173): 4.27e-24: 106: 28.77		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		121464 TR10A_HUMAN (30-173): 4.27e-24: 106: 28.77		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		120192 TR10A_HUMAN (30-173): 4.27e-24: 106: 28.77		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98