HitPredict

Interactor 1: ODO2 (P36957)
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K)
Gene: DLST

Interactor 2: FAKD3 (Q14CZ7)
FAST kinase domain-containing protein 3, mitochondrial
Gene: FASTKD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	32877691, 20869947
Identification Methods	proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 453 Hs			1 662
+	Hs
		505975 ODB2_HUMAN (32-453): 2.26e-147: 430: 24.24		FAKD3_HUMAN (1-662): 0: 713: 100.00
+	Hs
		739324 ODO2_HUMAN (1-453): 0: 538: 100.00		FAKD2_HUMAN (51-653): 3.99e-163: 486: 17.81
+	Hs
		739219 ODO2_HUMAN (1-453): 0: 538: 100.00		FAKD4_HUMAN (99-651): 5.86e-155: 463: 21.34
+	Hs
		739173 ODO2_HUMAN (1-453): 0: 538: 100.00		FAKD5_HUMAN (129-597): 5.17e-128: 398: 19.79
+	Hs
		506021 ODB2_HUMAN (32-453): 2.26e-147: 430: 24.24		FAKD4_HUMAN (99-651): 5.86e-155: 463: 21.34
+	Hs
		126263 ODPX_HUMAN (17-449): 1.53e-138: 408: 23.47		FAKD4_HUMAN (99-651): 5.86e-155: 463: 21.34
+	Hs
		505996 ODB2_HUMAN (32-453): 2.26e-147: 430: 24.24		FAKD5_HUMAN (129-597): 5.17e-128: 398: 19.79
+	Hs
		489785 ODP2_HUMAN (27-195): 1.31e-27: 117: 23.98		FAKD4_HUMAN (99-651): 5.86e-155: 463: 21.34
+	Hs
		489769 ODP2_HUMAN (27-195): 1.31e-27: 117: 23.98		FAKD5_HUMAN (129-597): 5.17e-128: 398: 19.79