Protein: WBP4
WW domain-binding protein 4 (WBP-4) (Formin-binding protein 21) (WW domain-containing-binding protein 4)

Gene: WBP4
Organism: Homo sapiens
Interactions: 114
UniProt ID: O75554

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

286427

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

6

Small-scale

0.845

High

286442

RUXF
Small nuclear ribonucleoprotein F

2

7

High-throughput

0.811

High

286443

LSM6
U6 snRNA-associated Sm-like protein LSm6

2

7

High-throughput

0.811

High

286447

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

8

High-throughput

0.811

High

286441

RUXE
Small nuclear ribonucleoprotein E

1

2

High-throughput

0.691

High

286444

SMD3
Small nuclear ribonucleoprotein Sm D3

1

6

High-throughput

0.691

High

286507

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

6

High-throughput

0.691

High

286512

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

6

High-throughput

0.691

High

163677

TCRG1
Transcription elongation regulator 1

1

8

High-throughput

0.681

High

286422

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

13

High-throughput

0.681

High

286450

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

3

7

Small-scale

0.665

High

286511

WBP11
WW domain-binding protein 11

3

4

Small-scale

0.665

High

286477

RBM45
RNA-binding protein 45

3

6

High-throughput

0.662

High

286416

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

2

17

Small-scale

0.655

High

209170

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

2

6

High-throughput

0.629

High

212115

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

2

2

High-throughput

0.629

High

286487

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

3

High-throughput

0.628

High

286469

SF3A1
Splicing factor 3A subunit 1

2

5

Small-scale

0.627

High

286468

SF3A2
Splicing factor 3A subunit 2

2

4

High-throughput

0.624

High

207384

DHX15
ATP-dependent RNA helicase DHX15

2

9

Small-scale

0.619

High

286440

HNRPK
Heterogeneous nuclear ribonucleoprotein K

2

10

Small-scale

0.619

High

286449

EWS
RNA-binding protein EWS

2

8

High-throughput

0.608

High

286423

SNRPA
U1 small nuclear ribonucleoprotein A

2

11

High-throughput

0.605

High

286483

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

2

11

High-throughput

0.605

High

286481

FSTL5
Follistatin-related protein 5

2

3

High-throughput

0.574

High

286433

COIL
Coilin

2

0

High-throughput

0.547

High

286430

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

5

Small-scale

0.541

High

286455

SF3B2
Splicing factor 3B subunit 2

1

3

Small-scale

0.541

High

286457

SNW1
SNW domain-containing protein 1

1

1

Small-scale

0.541

High

286489

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

9

Small-scale

0.541

High

286495

WDR83
WD repeat domain-containing protein 83

1

7

Small-scale

0.541

High

286504

ARGL1
Arginine and glutamate-rich protein 1

1

2

Small-scale

0.541

High

286482

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

1

High-throughput

0.536

High

286509

SET1B
Histone-lysine N-methyltransferase SETD1B

1

3

High-throughput

0.536

High

141233

DDX3X
ATP-dependent RNA helicase DDX3X

1

7

High-throughput

0.527

High

223479

ZN207
BUB3-interacting and GLEBS motif-containing protein ZNF207

1

3

High-throughput

0.527

High

224193

BUB3
Mitotic checkpoint protein BUB3

1

6

High-throughput

0.527

High

252396

DIAP1
Protein diaphanous homolog 1

1

6

High-throughput

0.527

High

285739

SF3B1
Splicing factor 3B subunit 1

1

5

High-throughput

0.527

High

286417

SCAF4
SR-related and CTD-associated factor 4

1

8

High-throughput

0.527

High

286425

PABP1
Polyadenylate-binding protein 1

1

5

High-throughput

0.527

High

286426

XRCC6
X-ray repair cross-complementing protein 6

1

3

High-throughput

0.527

High

286429

SFPQ
Splicing factor, proline- and glutamine-rich

1

11

High-throughput

0.527

High

286431

FUS
RNA-binding protein FUS

1

14

High-throughput

0.527

High

286434

WASP
Actin nucleation-promoting factor WAS

1

8

High-throughput

0.527

High

286448

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.527

High

286453

SF3A3
Splicing factor 3A subunit 3

1

2

High-throughput

0.527

High

286458

CAPR1
Caprin-1

1

3

High-throughput

0.527

High

286460

HLTF
Helicase-like transcription factor

1

5

High-throughput

0.527

High

286463

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.527

High

286466

SF3B3
Splicing factor 3B subunit 3

1

7

High-throughput

0.527

High

286473

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

17

High-throughput

0.527

High

286478

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

8

High-throughput

0.527

High

286488

PSPC1
Paraspeckle component 1

1

12

High-throughput

0.527

High

286497

DDX23
Probable ATP-dependent RNA helicase DDX23

1

10

High-throughput

0.527

High

286493

ZC21A
Zinc finger C2HC domain-containing protein 1A

1

0

Small-scale

0.518

High

286508

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

Small-scale

0.518

High

286510

FA50B
Protein FAM50B

1

0

Small-scale

0.518

High

286491

H2B1H
Histone H2B type 1-H

1

2

High-throughput

0.515

High

286501

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.513

High

215000

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.505

High

185296

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

225233

HTSF1
17S U2 SnRNP complex component HTATSF1

1

12

High-throughput

0.501

High

286465

NONO
Non-POU domain-containing octamer-binding protein

1

13

High-throughput

0.501

High

286467

SF3B4
Splicing factor 3B subunit 4

1

10

High-throughput

0.501

High

286471

SF01
Splicing factor 1

1

8

High-throughput

0.501

High

286503

TMM51
Transmembrane protein 51

1

1

High-throughput

0.489

High

219538

WIPF1
WAS/WASL-interacting protein family member 1

1

5

High-throughput

0.481

High

258025

IF2P
Eukaryotic translation initiation factor 5B

1

2

High-throughput

0.481

High

286128

CSDE1
Cold shock domain-containing protein E1

1

1

High-throughput

0.481

High

286438

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.481

High

286446

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

4

Small-scale

0.481

High

286456

SQSTM
Sequestosome-1

1

2

High-throughput

0.481

High

286476

LARP4
La-related protein 4

1

7

High-throughput

0.481

High

286486

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

1

High-throughput

0.481

High

286496

RBM42
RNA-binding protein 42

1

5

High-throughput

0.481

High

286502

RBM22
Pre-mRNA-splicing factor RBM22

1

8

High-throughput

0.481

High

286505

TFP11
Tuftelin-interacting protein 11

1

2

High-throughput

0.481

High

286424

CTF8
Chromosome transmission fidelity protein 8 homolog

1

0

High-throughput

0.480

High

286418

GCR
Glucocorticoid receptor

1

6

High-throughput

0.479

High

286419

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.479

High

286420

ADT2
ADP/ATP translocase 2

1

1

High-throughput

0.479

High

286421

HS90A
Heat shock protein HSP 90-alpha

1

4

High-throughput

0.479

High

286432

SYUA
Alpha-synuclein

1

2

Small-scale

0.479

High

286445

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.479

High

286451

EP300
Histone acetyltransferase p300

1

3

High-throughput

0.479

High

286452

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

7

High-throughput

0.479

High

286459

RBM39
RNA-binding protein 39

1

11

High-throughput

0.479

High

286464

EEA1
Early endosome antigen 1

1

1

High-throughput

0.479

High

286472

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.479

High

286474

Q5H919
HIV-1 Tat specific factor 1

1

13

High-throughput

0.479

High

286475

Q5SZ64
Splicing factor 3B subunit 4

1

6

High-throughput

0.479

High

286479

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

286492

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.479

High

286506

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

286490

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.460

High

286494

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.460

High

286499

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

286462

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

286498

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

286437

DYN2
Dynamin-2

1

3

High-throughput

0.457

High

216208

PPIH
Peptidyl-prolyl cis-trans isomerase H

1

4

Small-scale

0.457

High

286435

HD
Huntingtin

1

4

High-throughput

0.457

High

286428

PGAM1
Phosphoglycerate mutase 1

1

1

High-throughput

0.437

High

286461

Q14820
Splicing factor 1, isoform CRA_b

1

4

High-throughput

0.437

High

286480

Q8N1K8
cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2

1

3

High-throughput

0.437

High

286454

FOXD4
Forkhead box protein D4

1

0

High-throughput

0.426

High

231180

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

286436

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

0

High-throughput

0.279

Low

286439

FCGRN
IgG receptor FcRn large subunit p51

1

0

High-throughput

0.279

Low

286484

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.279

Low

286485

DOK4
Docking protein 4

1

0

High-throughput

0.279

Low

286500

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

0

High-throughput

0.279

Low

286470

Q15559

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025