Interactor 1: SRP14 (P37108)
Signal recognition particle 14 kDa protein (SRP14) (18 kDa Alu RNA-binding protein)
Gene: SRP14

Interactor 2: SRP09 (P49458)
Signal recognition particle 9 kDa protein (SRP9)
Gene: SRP9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 32296183, 30021884, 35271311, 34349018, 35235311, 37071682, 28514442, 11089964, 2153922, 33961781, 23221635, unassigned1304
Identification Methods two hybrid, proximity labelling technology, affinity chromatography technology, cross-linking study, x-ray crystallography, pull down, ion exchange chromatography, two hybrid prey pooling approach, two hybrid array, validated two hybrid and 1 others

more...

Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SRP14~SRP9-21
Common GO terms GO:0003723 - RNA binding
GO:0005786 - signal recognition particle, endoplasmic reticulum targeting
GO:0005829 - cytosol
GO:0006614 - SRP-dependent cotranslational protein targeting to membrane
GO:0008312 - 7S RNA binding
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 136
Hs

1 86
+ Dm
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024