Protein: HDAC1
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)

Gene: HDAC1
Organism: Drosophila melanogaster
Interactions: 79
UniProt ID: Q94517

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003714 - transcription corepressor activity
GO:0004407 - histone deacetylase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1276539

Q9VHB7
LD22928p

4

9

Small-scale

0.904

High

81423

B7Z0T5
Metastasis associated 1-like, isoform C

2

20

Small-scale

0.754

High

1123842

RCOR
REST corepressor

2

20

Small-scale

0.754

High

1097598

ESC
Polycomb protein esc

5

20

Small-scale

0.727

High

1099152

CAF1
Chromatin assembly factor 1 p55 subunit

4

20

Small-scale

0.701

High

332806

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

4

20

Small-scale

0.694

High

785632

EZ
Histone-lysine N-methyltransferase E(z)

3

20

Small-scale

0.685

High

1137165

Q5U0Y0
LD13852p

4

20

Small-scale

0.672

High

639968

PC
Polycomb group protein Pc

3

14

Small-scale

0.656

High

1276545

KDM5
Lysine-specific demethylase 5

3

18

Small-scale

0.640

High

1276555

LSDA
Possible lysine-specific histone demethylase 1

3

10

Small-scale

0.640

High

558385

GROU
Protein groucho

3

20

Small-scale

0.625

High

800656

SUV39
Histone-lysine N-methyltransferase Su(var)3-9

2

20

Small-scale

0.624

High

51892

A1Z6Z7
Uncharacterized protein, isoform A

1

20

High-throughput

0.618

High

1276547

Q9VNC2
Histone deacetylase

1

15

Small-scale

0.618

High

1000604

Q0E8J0
MEP-1, isoform A

2

9

Small-scale

0.611

High

1097856

PCL
Polycomb protein Pcl

1

18

Small-scale

0.586

High

1196991

Q86BH2
Grunge, isoform C

2

20

Small-scale

0.584

High

1276559

Q9W410
GH06635p

2

20

Small-scale

0.584

High

1276548

Q9VNF6
Metastasis associated 1-like, isoform A

1

20

High-throughput

0.575

High

1276552

Q9VTX2
RE32936p

1

4

Small-scale

0.561

High

87047

C6SV09
IP16414p

2

0

Small-scale

0.559

High

1096252

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.541

High

54074

LIN54
Protein lin-54 homolog

1

5

Small-scale

0.536

High

576068

JRA
Transcription factor Jra

1

16

Small-scale

0.536

High

1096416

STAT
Signal transducer and transcription activator

1

12

Small-scale

0.536

High

1098074

HMG2
High mobility group protein DSP1

1

18

Small-scale

0.536

High

1213314

FRU
Sex determination protein fruitless

1

20

Small-scale

0.536

High

1276554

Q9VUB5
UpSET, isoform A

1

7

Small-scale

0.536

High

668267

ABDA
Homeobox protein abdominal-A

1

9

High-throughput

0.481

High

950026

UBX
Homeotic protein ultrabithorax

1

6

High-throughput

0.481

High

68996

A8WHL4
Bonus, isoform B

1

20

Small-scale

0.479

High

87758

D1YSG4
CORL

1

5

Small-scale

0.479

High

112870

M9NEW2
Chameau, isoform B

1

10

Small-scale

0.479

High

114641

M9PD17
Gigas, isoform B

1

1

High-throughput

0.479

High

115159

M9PEA2
CDK2-associated protein 1, isoform B

1

6

Small-scale

0.479

High

115789

M9PGH7
G9a, isoform B

1

20

Small-scale

0.479

High

116005

M9PH39
histone acetyltransferase

1

20

Small-scale

0.479

High

585764

CI
Transcriptional activator cubitus interruptus

1

10

Small-scale

0.479

High

599218

FOSLA
Transcription factor kayak, isoforms A/B/F

1

20

Small-scale

0.479

High

656842

SUH
Suppressor of hairless protein

1

4

High-throughput

0.479

High

996071

GAGA
Transcription activator GAGA

1

19

Small-scale

0.479

High

1097528

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

9

High-throughput

0.479

High

1097627

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

20

Small-scale

0.479

High

1097886

RBF
Retinoblastoma family protein

1

12

Small-scale

0.479

High

1181078

Q7KMQ6
IP16020p

1

4

High-throughput

0.479

High

1276527

Q960V1
LD33361p

1

4

Small-scale

0.479

High

1276528

Q9NHX6
GRUNGE

1

20

Small-scale

0.479

High

1276529

SUZ12
Polycomb protein Su(z)12

1

3

Small-scale

0.479

High

1276530

Q9U8L5
Dorsocross1, isoform A

1

7

Small-scale

0.479

High

1276531

Q9V3B8
LD18634p

1

5

Small-scale

0.479

High

1276532

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

4

High-throughput

0.479

High

1276533

Q9VB52
LD05287p

1

14

Small-scale

0.479

High

1276534

Q9VCC9
LD23779p

1

20

High-throughput

0.479

High

1276536

Q9VDK5
Bonus, isoform A

1

20

Small-scale

0.479

High

1276537

Q9VF04
RE32990p

1

12

Small-scale

0.479

High

1276538

EXOSX
Exosome complex component 10 homolog

1

3

Small-scale

0.479

High

1276540

SMBT
Polycomb protein Sfmbt

1

12

Small-scale

0.479

High

1276541

Q9VKD5
Escl, isoform A

1

20

Small-scale

0.479

High

1276542

PIWI
Protein piwi

1

6

Small-scale

0.479

High

1276550

Q9VQ58
FI15207p1

1

2

High-throughput

0.479

High

1276551

Q9VR61
Ribosomal protein S6 kinase II, isoform A

1

8

High-throughput

0.479

High

1276558

Q9W1G7
LD21576p

1

2

High-throughput

0.479

High

1276560

Q9W5E2
EG:115C2.8 protein

1

2

Small-scale

0.479

High

1276561

EAF3
NuA4 complex subunit EAF3 homolog

1

11

Small-scale

0.479

High

820569

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.464

High

53821

A1Z921
Frazzled, isoform B

1

0

Small-scale

0.458

High

1248500

ASTRX
Gametocyte-specific factor 1 homolog

1

0

Small-scale

0.458

High

1276543

Q9VL20
Ovaries absent, isoform A

1

0

Small-scale

0.458

High

1276549

Q9VPY3
Charon

1

0

Small-scale

0.458

High

950398

H4
Histone H4

1

13

Small-scale

0.457

High

1276557

Q9VZ27
CDK2-associated protein 1, isoform A

1

6

Small-scale

0.445

High

1096786

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

9

Small-scale

0.437

High

1276553

AGT2L
Alanine--glyoxylate aminotransferase 2-like

1

1

High-throughput

0.437

High

1276535

EI3D1
Eukaryotic translation initiation factor 3 subunit D-1

1

0

Small-scale

0.426

High

184384

O17142
Transcriptional co-repressor SIN3A

1

20

High-throughput

0.381

High

1276544

Q9VM11
HL01515p

1

0

High-throughput

0.249

Low

1276546

ORCO
Odorant receptor coreceptor

1

0

Small-scale

0.249

Low

1276556

Q9VWJ6
FI03615p

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024