Interactor 1: FGF8 (P37237)
Fibroblast growth factor 8 (FGF-8) (Androgen-induced growth factor) (AIGF) (Heparin-binding growth factor 8) (HBGF-8)
Gene: FGF8

Interactor 2: FGFR3 (Q61851)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Heparin-binding growth factor receptor) (CD antigen CD333)
Gene: FGFR3

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10574949
Identification Methods biochemical
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FGF~I-set, FGF~Ig_3
Common GO terms GO:0000165 - MAPK cascade
GO:0008283 - cell population proliferation
GO:0008284 - positive regulation of cell population proliferation
GO:0008543 - fibroblast growth factor receptor signaling pathway
GO:0050731 - positive regulation of peptidyl-tyrosine phosphorylation
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 268
Mm

1 801
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Last updated: 15 Jul 2024