HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	36634849, 11698390, 17893145, 16216085, 32814053
Identification Methods	proximity labelling technology, affinity chromatography technology, unspecified method, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 451
+	Hs
		742367 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Mm
		223022 SYUA_MOUSE (1-140): 4.44e-57: 175: 95.00		TBA3_MOUSE (1-440): 0: 713: 97.73
+	Hs
		428061 SYUA_HUMAN (1-140): 5.01e-57: 175: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.23