HitPredict

Interactor 1: RAD23 (P32628)
UV excision repair protein RAD23
Gene: RAD23

Interactor 2: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	11805826, 12198498, 37968396, 16429126
Identification Methods	tandem affinity purification, pull down, affinity chromatography technology
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 398 Sc			1 523
+	Rn
		64478 RD23B_RAT (2-398): 7.82e-92: 284: 27.50		A6HIT6_RAT (4-513): 0: 545: 30.21
+	Hs
		210901 RD23B_HUMAN (2-398): 5.12e-90: 279: 27.50		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		210900 RD23A_HUMAN (2-398): 3.39e-87: 270: 28.09		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		211082 UBQL1_HUMAN (1-373): 1.05e-58: 202: 12.53		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		211074 UBQL2_HUMAN (1-373): 8.72e-55: 192: 12.65		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		211057 UBQL4_HUMAN (2-373): 1.17e-52: 186: 13.76		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Mm
		574845 UBQL2_MOUSE (1-373): 3.82e-50: 180: 11.79		PSMD3_MOUSE (4-513): 0: 545: 30.21
+	Dm
		669739 Q9VWD9_DROME (2-374): 1.82e-47: 171: 13.38		PSMD3_DROME (1-513): 0: 521: 31.40
+	Hs
		210917 RS27A_HUMAN (2-89): 1.27e-38: 137: 22.73		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		1154963 NEDD8_HUMAN (2-62): 2.69e-15: 72.3: 24.59		CSN3_HUMAN (186-500): 7.71e-119: 358: 19.57