HitPredict

Interactor 1: TRS20 (P38334)
Trafficking protein particle complex subunit 20 (TRAPP subunit 20) (Transport protein particle 20 kDa subunit)
Gene: TRS20

Interactor 2: TR130 (Q03660)
Trafficking protein particle complex II-specific subunit 130 (TRAPP II-specific subunit 130) (Transport protein particle 130 kDa subunit)
Gene: TRS130

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	11805826, 27872253, 30528786, 16429126, 37968396, 21453443
Identification Methods	tandem affinity purification, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006891 - intra-Golgi vesicle-mediated transport GO:0016236 - macroautophagy GO:0042147 - retrograde transport, endosome to Golgi GO:1990071 - TRAPPII protein complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 175 Sc			1 1102
+	Dm
		1365344 TPPC2_DROME (2-173): 2.37e-43: 142: 29.65		TPC10_DROME (11-464): 3.8e-146: 469: 15.49
+	Hs
		483236 TPC2A_HUMAN (4-173): 6.69e-48: 154: 33.53		TPC10_HUMAN (11-465): 2.72e-139: 454: 18.56
+	Hs
		483293 TPC2B_HUMAN (4-173): 6.69e-48: 154: 33.53		TPC10_HUMAN (11-465): 2.72e-139: 454: 18.56
+	Dm
		53203 A1Z8I0_DROME (1-168): 9.66e-42: 138: 22.02		TPC10_DROME (11-464): 3.8e-146: 469: 15.49
+	Hs
		819737 TPC2L_HUMAN (1-168): 9.44e-43: 141: 26.04		TPC10_HUMAN (11-465): 2.72e-139: 454: 18.56