HitPredict

Interactor 1: HSM3 (P38348)
DNA mismatch repair protein HSM3 (Enhanced spontaneous mutability protein 3)
Gene: HSM3

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	1.00	0.956

Property	Details
Experiments	11805826, 19217412, 19446323, 37968396, 20471945, 19446322, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA_lid_3~HSM3_C, AAA_lid_3~HSM3_N
Common GO terms	GO:0005634 - nucleus GO:0070682 - proteasome regulatory particle assembly
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 480 Sc			1 405
+	Sc
		748945 HSM3_YEAST (1-480): 0: 965: 100.00		PRS4_YEAST (72-395): 3.99e-106: 321: 49.85
+	Sc
		703884 HSM3_YEAST (1-480): 0: 965: 100.00		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78