HitPredict

Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30804502, 16628214
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1863 Hs			1 103
+	Hs
		917671 TOPB1_HUMAN (1122-1861): 3.79e-150: 505: 14.12		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917618 MCPH1_HUMAN (1150-1857): 1.33e-95: 331: 14.19		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		536778 TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917809 BARD1_HUMAN (13-366): 4.46e-32: 137: 11.98		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917882 TRI31_HUMAN (15-120): 1.69e-29: 125: 28.30		H4_HUMAN (1-103): 1.38e-48: 151: 100.00