Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Interactor 2: BRAT1 (Q6PJG6)
BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1)
Gene: BRAT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.55 0.611

The method score is based on:

Property Details
Experiments 16452482, 24073851
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, two hybrid, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
GO:0010212 - response to ionizing radiation
Homologous interactions 0

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Last updated: 15 Jul 2024