HitPredict

Interactor 1: PPZ2 (P33329)
Serine/threonine-protein phosphatase PP-Z2 (EC 3.1.3.16)
Gene: PPZ2

Interactor 2: SIS2 (P36024)
Phosphopantothenoylcysteine decarboxylase subunit SIS2 (Halotolerance protein HAL3) (Sit4 suppressor 2)
Gene: SIS2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	18467557, 37968396, 20489023
Identification Methods	protein complementation assay, affinity chromatography technology, anti tag coimmunoprecipitation, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 710 Sc			1 562
+	Sc
		751630 PPZ2_YEAST (1-710): 0: 1054: 100.00		VHS3_YEAST (43-492): 1.41e-171: 503: 45.81
+	Sc
		687045 PPZ1_YEAST (30-710): 0: 838: 59.29		SIS2_YEAST (1-562): 0: 688: 100.00
+	Sc
		751612 PPZ2_YEAST (1-710): 0: 1054: 100.00		CAB3_YEAST (169-502): 3.96e-101: 318: 29.89
+	Sc
		687086 PPZ1_YEAST (30-710): 0: 838: 59.29		VHS3_YEAST (43-492): 1.41e-171: 503: 45.81
+	Sc
		687048 PPZ1_YEAST (30-710): 0: 838: 59.29		CAB3_YEAST (169-502): 3.96e-101: 318: 29.89
+	Ca
		1202736 Q59U06_CANAL (294-706): 0: 538: 66.59		Q5A868_CANAL (172-528): 1.3e-94: 306: 30.61
+	Sp
		1009088 PPZ_SCHPO (393-703): 5.04e-168: 494: 73.31		TYSY_SCHPO (261-511): 1.25e-82: 272: 34.36