HitPredict

Interactor 1: FEOB (P33650)
Fe(2+) transporter FeoB (Ferrous iron transport protein B)
Gene: FEOB

Interactor 2: FEOB (P33650)
Fe(2+) transporter FeoB (Ferrous iron transport protein B)
Gene: FEOB

Species: Escherichia coli K-12

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.841

Property	Details
Experiments	24561554, 19629046
Identification Methods	two hybrid, affinity chromatography technology, x-ray crystallography, cross-linking study, two hybrid array, pull down, luminescence based mammalian interactome mapping
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	FeoB_Cyto~FeoB_Cyto, FeoB_Cyto~FeoB_N, FeoB_N~FeoB_N
Common GO terms	GO:0005525 - GTP binding GO:0005886 - plasma membrane GO:0006974 - DNA damage response GO:0015093 - ferrous iron transmembrane transporter activity GO:0098711 - iron ion import across plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 773 Ec			1 773
+	Hp
		202469 FEOB_HELPY (1-712): 0: 631: 26.30		FEOB_HELPY (1-712): 0: 631: 26.30
+	Hs
		61995 MTG2_HUMAN (7-181): 3.12e-40: 155: 27.03		GTPBA_HUMAN (6-183): 2.22e-33: 134: 20.74
+	Sc
		1039611 NOG1_YEAST (5-195): 1.41e-34: 142: 15.76		NOG1_YEAST (5-195): 1.41e-34: 142: 15.76
+	Aa
		266350 MNME_AQUAE (3-236): 4.56e-35: 140: 22.79		MNME_AQUAE (3-236): 4.56e-35: 140: 22.79
+	Ns
		1362131 MNME_NOSS1 (2-175): 1.04e-32: 134: 21.02		MNME_NOSS1 (2-175): 1.04e-32: 134: 21.02
+	Vc
		1440957 OBG_VIBCH (6-166): 1.71e-32: 132: 14.29		OBG_VIBCH (6-166): 1.71e-32: 132: 14.29
+	Hs
		1381640 MTG2_HUMAN (7-181): 3.12e-40: 155: 27.03		GTPB3_HUMAN (4-168): 1.28e-16: 85.5: 19.77
+	Ec
		676564 MNME_ECOLI (4-164): 6.83e-24: 107: 19.76		MNME_ECOLI (4-164): 6.83e-24: 107: 19.76
+	Hs
		1381628 GTPB3_HUMAN (4-168): 1.28e-16: 85.5: 19.77		GTPB3_HUMAN (4-168): 1.28e-16: 85.5: 19.77