HitPredict

Interactor 1: RPF1 (P38805)
Ribosome production factor 1 (Ribosome biogenesis protein RPF1)
Gene: RPF1

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.848

Property	Details
Experiments	29557065, 16429126, 37968396
Identification Methods	biochemical, x-ray crystallography, affinity chromatography technology, tandem affinity purification
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	Brix~Brix
Common GO terms	GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor GO:0042134 - rRNA primary transcript binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 295 Sc			1 291
+	Sc
		733817 RPF1_YEAST (1-295): 8.87e-130: 372: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		755284 RPF1_YEAST (1-295): 8.87e-130: 372: 100.00		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Sc
		733892 IMP4_YEAST (22-295): 1.85e-108: 318: 26.96		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		754857 RPF1_YEAST (1-295): 8.87e-130: 372: 100.00		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		755350 RPF1_YEAST (1-295): 8.87e-130: 372: 100.00		SSF2_YEAST (10-197): 8.32e-33: 127: 15.17