HitPredict

Interactor 1: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Interactor 2: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 857 Hs			1 621
+	Hs
		899916 KPCD1_HUMAN (175-857): 6.92e-134: 423: 15.61		FXR1_HUMAN (1-621): 0: 998: 100.00
+	Hs
		900143 KPCD2_HUMAN (140-855): 1.38e-118: 382: 14.66		FXR1_HUMAN (1-621): 0: 998: 100.00
+	Mm
		1222202 PAK3_MOUSE (237-805): 5.69e-121: 379: 18.44		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Mm
		109229 G5E884_MOUSE (239-800): 8.39e-119: 372: 18.04		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Mm
		312742 PAK1_MOUSE (239-800): 4.34e-117: 368: 18.39		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Hs
		900231 KCC2A_HUMAN (525-856): 3.54e-95: 308: 22.13		FXR1_HUMAN (1-621): 0: 998: 100.00
+	Hs
		900339 KPCD1_HUMAN (175-857): 6.92e-134: 423: 15.61		FXR2_HUMAN (4-621): 0: 840: 57.75
+	Mm
		548950 KCC2A_MOUSE (525-856): 6.37e-95: 307: 21.84		FXR1_MOUSE (1-621): 0: 950: 88.77
+	Hs
		900313 KCC2D_HUMAN (519-856): 1.1e-113: 357: 22.95		FXR2_HUMAN (4-621): 0: 840: 57.75
+	Mm
		616111 KS6A1_MOUSE (477-790): 2.55e-67: 239: 20.77		FXR2_MOUSE (4-621): 0: 810: 56.12
+	Mm
		1223540 KPCD1_MOUSE (157-853): 1.34e-133: 423: 15.35		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		777905 KPCD1_MOUSE (157-853): 1.34e-133: 423: 15.35		FMR1_MOUSE (1-506): 0: 599: 51.04
+	Mm
		1297146 PAK5_MOUSE (137-798): 3.4e-118: 376: 15.19		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		1244503 KCC2D_MOUSE (519-856): 1.1e-113: 357: 22.95		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Mm
		777961 PAK5_MOUSE (137-798): 3.4e-118: 376: 15.19		FMR1_MOUSE (1-506): 0: 599: 51.04
+	Mm
		777929 KCC2D_MOUSE (519-856): 1.1e-113: 357: 22.95		FMR1_MOUSE (1-506): 0: 599: 51.04
+	Mm
		548966 KCC2A_MOUSE (525-856): 6.37e-95: 307: 21.84		Q8BPK8_MOUSE (1-334): 0: 618: 73.95
+	Hs
		1057055 KCC2A_HUMAN (525-856): 3.54e-95: 308: 22.13		FMR1_HUMAN (1-506): 0: 599: 51.13
+	Mm
		548936 KCC2A_MOUSE (525-856): 6.37e-95: 307: 21.84		FMR1_MOUSE (1-506): 0: 599: 51.04