HitPredict

Interactor 1: KOG1 (P38873)
Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24) (Regulatory-associated protein of TOR) (Raptor)
Gene: KOG1

Interactor 2: RAGAB (Q00582)
GTP-binding protein GTR1 (EC 3.6.5.-)
Gene: GTR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.740

Property	Details
Experiments	24702707, 23716719, 19748353, 22424774, 30485160, 33566094, 24514902
Identification Methods	two hybrid, affinity chromatography technology, pull down, protein complementation assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0005737 - cytoplasm GO:0009267 - cellular response to starvation
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1557 Sc			1 310
+	Sc
		756543 KOG1_YEAST (1-1557): 0: 1428: 100.00		RAGCD_YEAST (2-299): 3.73e-98: 294: 22.40
+	Hs
		1184605 RPTOR_HUMAN (20-1552): 0: 1188: 28.59		RRAGA_HUMAN (2-310): 2.25e-132: 380: 50.96
+	Hs
		1230044 RPTOR_HUMAN (20-1552): 0: 1188: 28.59		RRAGC_HUMAN (4-310): 3.09e-128: 372: 21.38
+	Hs
		1230047 RPTOR_HUMAN (20-1552): 0: 1188: 28.59		RRAGD_HUMAN (2-310): 1.29e-127: 371: 20.94
+	Hs
		1139770 RPTOR_HUMAN (20-1552): 0: 1188: 28.59		RRAGB_HUMAN (2-310): 5.54e-127: 369: 47.06
+	Sp
		252104 MIP1_SCHPO (796-1554): 1.39e-75: 279: 31.21		RAGAB_SCHPO (5-310): 7.76e-122: 353: 51.78