Interactor 1: RPN10 (P38886)
26S proteasome regulatory subunit RPN10
Gene: RPN10

Interactor 2: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.992

The method score is based on:

Property Details
Experiments 11805826, 17978571, 16429126, 17499717, 20941496, 14759368, 16284124, 16338358, 22215586, 24038880, 26450923, 26601941, 12408819, 16554755, 26182356, 28106073, 26929360, 19153599, 37968396, 34161281 and 10 others

more...

Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~VWA_2
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043248 - proteasome assembly
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 268
Sc

1 306
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs

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Last updated: 15 Jul 2024