HitPredict - High confidence protein-protein interactions

Interactor 1: CENPN (P38907)
Inner kinetochore subunit CHL4 (CENP-N homolog) (Chromosome loss protein 4) (Chromosome transmission fidelity protein 17) (Constitutive centromere-associated network protein CHL4) (Minichromosome maintenance protein 17)
Gene: CHL4

Interactor 2: CENPN (P38907)
Inner kinetochore subunit CHL4 (CENP-N homolog) (Chromosome loss protein 4) (Chromosome transmission fidelity protein 17) (Constitutive centromere-associated network protein CHL4) (Minichromosome maintenance protein 17)
Gene: CHL4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.90	0.728

Property	Details
Experiments	24311582, 31112132
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	CENP-N~CENP-N
Common GO terms	GO:0000776 - kinetochore GO:0000940 - outer kinetochore GO:0005198 - structural molecule activity GO:0005634 - nucleus GO:0007059 - chromosome segregation and 10 others more... GO:0007094 - mitotic spindle assembly checkpoint signaling GO:0008608 - attachment of spindle microtubules to kinetochore GO:0034080 - CENP-A containing chromatin assembly GO:0034087 - establishment of mitotic sister chromatid cohesion GO:0034089 - establishment of meiotic sister chromatid cohesion GO:0034090 - maintenance of meiotic sister chromatid cohesion GO:0051301 - cell division GO:0051321 - meiotic cell cycle GO:0051382 - kinetochore assembly GO:0071459 - protein localization to chromosome, centromeric region
Homologous interactions	0

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Last updated: 15 Jul 2024