HitPredict

Interactor 1: FKBP3 (P38911)
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (FK506-binding nuclear protein) (FKBP-70) (Nucleolar proline isomerase) (Proline rotamase)
Gene: FPR3

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	37968396, 28183979
Identification Methods	affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 411 Sc			1 291
+	Sc
		986480 FKBP4_YEAST (1-410): 6.37e-110: 330: 53.16		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Sp
		251203 FKBP4_SCHPO (5-410): 7.94e-88: 272: 38.20		BRX1_SCHPO (1-286): 4.18e-89: 268: 50.84
+	Sc
		733939 FKBP4_YEAST (1-410): 6.37e-110: 330: 53.16		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		733823 FKBP3_YEAST (1-411): 1.34e-108: 327: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		755332 FKBP4_YEAST (1-410): 6.37e-110: 330: 53.16		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Sc
		755285 FKBP3_YEAST (1-411): 1.34e-108: 327: 100.00		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Dm
		870400 FKB39_DROME (81-410): 2.96e-75: 240: 28.09		BRX1_DROME (8-291): 5.37e-82: 253: 40.91
+	Sp
		251209 FKBP4_SCHPO (5-410): 7.94e-88: 272: 38.20		RPF2_SCHPO (4-280): 1.39e-59: 194: 13.47
+	Sc
		754914 FKBP4_YEAST (1-410): 6.37e-110: 330: 53.16		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		754858 FKBP3_YEAST (1-411): 1.34e-108: 327: 100.00		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Dm
		870363 FKB39_DROME (81-410): 2.96e-75: 240: 28.09		Q9VBY2_DROME (3-255): 4.92e-67: 212: 18.61
+	Dm
		870368 FKB39_DROME (81-410): 2.96e-75: 240: 28.09		RPF2_DROME (3-288): 1.6e-60: 196: 16.67
+	Hs
		1034999 FKBP5_HUMAN (168-410): 1.69e-56: 194: 17.65		RPF2_HUMAN (1-285): 3.52e-77: 238: 17.57