HitPredict

Interactor 1: DYN2 (P39054)
Dynamin-2 (EC 3.6.5.5) (Dynamin UDNM)
Gene: Dnm2

Interactor 2: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.726

The method score is based on:

Property Details
Experiments 15102471, 23452850
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~SH3_1
Common GO terms GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0017124 - SH3 domain binding
GO:0031623 - receptor internalization
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 870
Mm

1 217
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024