HitPredict

Interactor 1: COIA1 (P39060)
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)]
Gene: COL18A1

Interactor 2: C1QL4 (Q86Z23)
Complement C1q-like protein 4 (C1q and tumor necrosis factor-related protein 11) (C1q/TNF-related protein 11)
Gene: C1QL4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005581 - collagen trimer GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1754 Hs			1 238
+	Hs
		760531 COIA1_HUMAN (1-1754): 0: 1036: 99.60		ADIPO_HUMAN (10-238): 5.47e-54: 175: 32.63
+	Hs
		362515 COIA1_HUMAN (1-1754): 0: 1036: 99.60		C1QB_HUMAN (31-238): 3.25e-51: 168: 31.39
+	Hs
		760557 COIA1_HUMAN (1-1754): 0: 1036: 99.60		C1QT1_HUMAN (14-237): 5.14e-44: 151: 26.70
+	Hs
		760558 COIA1_HUMAN (1-1754): 0: 1036: 99.60		C1QT7_HUMAN (29-238): 2.59e-43: 149: 28.63
+	Hs
		362584 COIA1_HUMAN (1-1754): 0: 1036: 99.60		C1QC_HUMAN (22-238): 2.52e-41: 143: 31.34
+	Hs
		760534 COIA1_HUMAN (1-1754): 0: 1036: 99.60		Q4VAQ0_HUMAN (24-237): 1.07e-33: 127: 29.96
+	Hs
		70507 COIA1_HUMAN (1-1754): 0: 1036: 99.60		C1T9B_HUMAN (31-144): 1.09e-14: 73.8: 22.41
+	Hs
		473745 COIA1_HUMAN (1-1754): 0: 1036: 99.60		C1T9A_HUMAN (51-150): 9.17e-11: 62.6: 23.00
+	Hs
		358667 CO4A1_HUMAN (783-1673): 7.78e-70: 262: 22.25		C1QT1_HUMAN (14-237): 5.14e-44: 151: 26.70
+	Hs
		362501 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		C1QB_HUMAN (31-238): 3.25e-51: 168: 31.39
+	Hs
		441079 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		C1QT1_HUMAN (14-237): 5.14e-44: 151: 26.70
+	Hs
		441080 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		C1QT2_HUMAN (28-238): 6.14e-44: 150: 30.09
+	Hs
		358641 CO3A1_HUMAN (594-1487): 3.12e-59: 227: 27.80		C1QT1_HUMAN (14-237): 5.14e-44: 151: 26.70
+	Hs
		362576 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		C1QC_HUMAN (22-238): 2.52e-41: 143: 31.34
+	Hs
		441066 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		Q4VAQ0_HUMAN (24-237): 1.07e-33: 127: 29.96
+	Hs
		441061 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		COAA1_HUMAN (90-237): 6.92e-26: 107: 29.80
+	Hs
		441048 CO4A2_HUMAN (875-1671): 4.08e-60: 231: 24.21		C1T9A_HUMAN (51-150): 9.17e-11: 62.6: 23.00
+	Hs
		358582 CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83		C1QC_HUMAN (22-238): 2.52e-41: 143: 31.34
+	Hs
		70495 CO2A1_HUMAN (1236-1673): 2.7e-27: 123: 17.83		C1T9B_HUMAN (31-144): 1.09e-14: 73.8: 22.41
+	Mm
		1144386 CO7A1_MOUSE (1240-1670): 7.73e-28: 125: 16.89		CO7A1_MOUSE (36-105): 8.91e-09: 57.4: 53.33