Interactor 1: GLYM (P34897)
Serine hydroxymethyltransferase, mitochondrial (SHMT) (EC 2.1.2.1) (Glycine hydroxymethyltransferase) (Serine methylase)
Gene: SHMT2

Interactor 2: ABRX2 (Q15018)
BRISC complex subunit Abraxas 2 (Abraxas brother protein 1) (Protein FAM175B)
Gene: ABRAXAS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 24075985, 28514442, 31142841, 31253574, 33961781
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MPN_2A_DUB_like~SHMT
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0070536 - protein K63-linked deubiquitination
GO:0070552 - BRISC complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 504
Hs

1 415
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025