Protein: ABRX2
BRISC complex subunit Abraxas 2 (Abraxas brother protein 1) (Protein FAM175B)

Gene: ABRX2, ABRAXAS2
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q15018

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000922 - spindle pole
GO:0002931 - response to ischemia
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

858774

BRCC3
Lys-63-specific deubiquitinase BRCC36

14

3

Small-scale

0.981

High

1136955

BABA2
BRISC and BRCA1-A complex member 2

9

1

Small-scale

0.970

High

760919

GLYM
Serine hydroxymethyltransferase, mitochondrial

5

1

Small-scale

0.924

High

1136954

BABA1
BRISC and BRCA1-A complex member 1

11

1

Small-scale

0.755

High

413854

P53
Cellular tumor antigen p53

5

0

Small-scale

0.691

High

255522

CYTIP
Cytohesin-interacting protein

3

1

High-throughput

0.667

High

968924

PRS8
26S proteasome regulatory subunit 8

3

4

Small-scale

0.662

High

132046

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

3

3

Small-scale

0.656

High

1136902

TENS2
Tensin-2

3

3

High-throughput

0.656

High

507996

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

3

Small-scale

0.655

High

1136924

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

1

Small-scale

0.639

High

1136908

TRAF7
E3 ubiquitin-protein ligase TRAF7

3

0

High-throughput

0.638

High

1136916

ARRD1
Arrestin domain-containing protein 1

3

0

High-throughput

0.638

High

1136928

THA11
THAP domain-containing protein 11

3

0

High-throughput

0.638

High

1136945

DEFI6
Differentially expressed in FDCP 6 homolog

3

0

High-throughput

0.638

High

760830

GLYC
Serine hydroxymethyltransferase, cytosolic

1

1

Small-scale

0.618

High

535841

LAMC1
Laminin subunit gamma-1

3

1

High-throughput

0.609

High

216440

SUV91
Histone-lysine N-methyltransferase SUV39H1

2

0

High-throughput

0.602

High

1134791

ODFP1
Outer dense fiber protein 1

2

0

High-throughput

0.602

High

1136895

STK11
Serine/threonine-protein kinase STK11

2

0

High-throughput

0.602

High

1136951

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

2

0

High-throughput

0.585

High

1136929

DCNL1
DCN1-like protein 1

2

0

High-throughput

0.580

High

906523

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

2

Small-scale

0.575

High

1136910

CSN6
COP9 signalosome complex subunit 6

1

1

Small-scale

0.575

High

1136923

CSN5
COP9 signalosome complex subunit 5

1

4

Small-scale

0.575

High

1136920

ARH40
Rho guanine nucleotide exchange factor 40

2

0

High-throughput

0.547

High

1134583

NUMA1
Nuclear mitotic apparatus protein 1

1

0

Small-scale

0.537

High

1136915

TENS4
Tensin-4

1

2

High-throughput

0.536

High

1136936

UIMC1
BRCA1-A complex subunit RAP80

1

1

High-throughput

0.536

High

1136948

TENS1
Tensin-1

1

3

High-throughput

0.536

High

124919

GTPB1
GTP-binding protein 1

1

0

High-throughput

0.513

High

789116

NUP62
Nuclear pore glycoprotein p62

1

0

High-throughput

0.513

High

849173

KSYK
Tyrosine-protein kinase SYK

1

0

High-throughput

0.513

High

987648

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.513

High

1136901

BSPRY
B box and SPRY domain-containing protein

1

0

High-throughput

0.513

High

1136905

KLH10
Kelch-like protein 10

1

0

High-throughput

0.513

High

1136913

DPP9
Dipeptidyl peptidase 9

1

0

High-throughput

0.513

High

1136919

POC1B
POC1 centriolar protein homolog B

1

0

High-throughput

0.513

High

1136926

ZN653
Zinc finger protein 653

1

0

High-throughput

0.513

High

1136942

TBB2B
Tubulin beta-2B chain

1

0

High-throughput

0.513

High

1136960

T22D4
TSC22 domain family protein 4

1

0

High-throughput

0.513

High

1136947

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

3

High-throughput

0.508

High

185710

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

1136939

FERM1
Fermitin family homolog 1

1

0

High-throughput

0.493

High

1136944

DJC25
DnaJ homolog subfamily C member 25

1

1

High-throughput

0.489

High

1136911

THAP5
THAP domain-containing protein 5

1

1

Small-scale

0.481

High

172826

XPO1
Exportin-1

1

1

High-throughput

0.479

High

269959

AUXI
Auxilin

1

2

High-throughput

0.479

High

617222

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

2

Small-scale

0.479

High

1136927

OPTN
Optineurin

1

1

High-throughput

0.479

High

1136943

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

Small-scale

0.479

High

1136957

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1136959

SH2B3
SH2B adapter protein 3

1

3

Small-scale

0.479

High

177225

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

0

High-throughput

0.458

High

241713

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

588728

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

695490

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

830757

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1136909

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1136918

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

0

High-throughput

0.458

High

1136925

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.458

High

1136931

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1136933

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1136935

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

0

Small-scale

0.458

High

1136946

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1136949

NGB
Neuroglobin

1

0

High-throughput

0.458

High

1136950

DCP1A
mRNA-decapping enzyme 1A

1

0

High-throughput

0.458

High

1136953

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

127965

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

4

Small-scale

0.445

High

128233

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

3

Small-scale

0.445

High

138924

USP9Y
Ubiquitin carboxyl-terminal hydrolase 9Y

1

1

Small-scale

0.445

High

210950

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

Small-scale

0.445

High

295503

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

1

Small-scale

0.445

High

610333

PRS6A
26S proteasome regulatory subunit 6A

1

5

Small-scale

0.445

High

778683

PRS7
26S proteasome regulatory subunit 7

1

3

Small-scale

0.445

High

851322

PRS6B
26S proteasome regulatory subunit 6B

1

3

Small-scale

0.445

High

968706

PRS4
26S proteasome regulatory subunit 4

1

3

Small-scale

0.445

High

1097986

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

Small-scale

0.445

High

1136519

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

2

Small-scale

0.445

High

1136912

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

Small-scale

0.445

High

1136937

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

1

Small-scale

0.445

High

1136940

PAAF1
Proteasomal ATPase-associated factor 1

1

1

Small-scale

0.445

High

1136941

CSN4
COP9 signalosome complex subunit 4

1

1

Small-scale

0.445

High

1136958

CSN3
COP9 signalosome complex subunit 3

1

4

Small-scale

0.445

High

165331

PSA7
Proteasome subunit alpha type-7

1

0

Small-scale

0.426

High

1136896

PSMD5
26S proteasome non-ATPase regulatory subunit 5

1

0

Small-scale

0.426

High

1136897

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.426

High

1136900

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

0

Small-scale

0.426

High

1136938

CSN8
COP9 signalosome complex subunit 8

1

0

Small-scale

0.426

High

1136952

PDLI7
PDZ and LIM domain protein 7

1

0

High-throughput

0.426

High

1136956

CSN7A
COP9 signalosome complex subunit 7a

1

0

Small-scale

0.426

High

379248

IGHG1
Immunoglobulin heavy constant gamma 1

1

1

High-throughput

0.407

High

379352

IGHG2
Immunoglobulin heavy constant gamma 2

1

1

High-throughput

0.407

High

1136898

Q59EL2
COP9 signalosome complex subunit 2

1

4

Small-scale

0.407

High

1136899

LRC73
Leucine-rich repeat-containing protein 73

1

1

High-throughput

0.407

High

1136961

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

3

0

High-throughput

0.347

High

1136932

TAFA4
Chemokine-like protein TAFA-4

2

0

High-throughput

0.328

High

1136934

CI085
Uncharacterized protein C9orf85

2

0

High-throughput

0.313

High

1010464

EREP3
Protein ENTREP3

1

0

High-throughput

0.279

Low

1108880

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

1

0

High-throughput

0.279

Low

1136904

ISK14
Serine protease inhibitor Kazal-type 14

1

0

High-throughput

0.279

Low

1136906

B4GN3
Beta-1,4-N-acetylgalactosaminyltransferase 3

1

0

High-throughput

0.279

Low

1136907

XKR2
XK-related protein 2

1

0

High-throughput

0.279

Low

1136917

CMIP6
Ciliary microtubule inner protein 6

1

0

High-throughput

0.279

Low

1136922

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

1136930

LOXL4
Lysyl oxidase homolog 4

1

0

High-throughput

0.279

Low

377574

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

768225

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1136903

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.249

Low

1136921

DNJB3
DnaJ homolog subfamily B member 3

1

0

High-throughput

0.249

Low

935734

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.232

Low

1048355

ACVR1
Activin receptor type-1

1

0

High-throughput

0.232

Low

1136914

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025