HitPredict

Interactor 1: TCPZ (P39079)
T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta)
Gene: CCT6

Interactor 2: HOS2 (P53096)
Probable histone deacetylase HOS2 (EC 3.5.1.98)
Gene: HOS2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 546 Sc			1 452
+	Hs
		1038583 TCPW_HUMAN (2-542): 0: 589: 54.53		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		1038670 TCPH_HUMAN (2-544): 0: 555: 25.73		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		826651 TCPG_HUMAN (2-546): 0: 549: 25.87		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		821200 TCPE_HUMAN (2-541): 0: 547: 25.74		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		826803 TCPG_HUMAN (2-546): 0: 549: 25.87		HDAC2_HUMAN (17-447): 0: 574: 45.85
+	Hs
		821342 TCPE_HUMAN (2-541): 0: 547: 25.74		HDAC2_HUMAN (17-447): 0: 574: 45.85
+	Sp
		140559 TCPZ_SCHPO (3-545): 0: 589: 59.48		PHD1_SCHPO (24-425): 0: 518: 57.96
+	Hs
		770823 TCPZ_HUMAN (2-542): 0: 526: 56.56		HDAC1_HUMAN (22-434): 0: 578: 48.56
+	Hs
		770965 TCPZ_HUMAN (2-542): 0: 526: 56.56		HDAC2_HUMAN (17-447): 0: 574: 45.85
+	Hs
		177367 TCPH_HUMAN (2-544): 0: 555: 25.73		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Hs
		177233 TCPG_HUMAN (2-546): 0: 549: 25.87		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Hs
		177231 TCPE_HUMAN (2-541): 0: 547: 25.74		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Sc
		693019 TCPZ_YEAST (1-546): 0: 531: 100.00		RPD3_YEAST (10-439): 0: 546: 44.60
+	Sp
		140638 TCPH_SCHPO (1-546): 0: 549: 25.05		PHD1_SCHPO (24-425): 0: 518: 57.96
+	Hs
		177216 TCPZ_HUMAN (2-542): 0: 526: 56.56		HDAC3_HUMAN (26-446): 0: 541: 50.12
+	Sp
		140519 TCPG_SCHPO (2-539): 0: 540: 26.02		PHD1_SCHPO (24-425): 0: 518: 57.96
+	Sp
		140725 TCPE_SCHPO (8-539): 0: 529: 27.53		PHD1_SCHPO (24-425): 0: 518: 57.96
+	Mm
		945920 TCPH_MOUSE (2-544): 0: 561: 25.73		HDAC4_MOUSE (2-423): 9.4e-145: 442: 23.09
+	Mm
		945965 TCPE_MOUSE (2-541): 0: 540: 25.55		HDAC4_MOUSE (2-423): 9.4e-145: 442: 23.09
+	Hs
		821140 TCPE_HUMAN (2-541): 0: 547: 25.74		HDAC4_HUMAN (2-423): 5.68e-141: 432: 22.17