HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: MT21A (Q8WXB1)
Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A)
Gene: METTL21A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 23349634
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 218
+	Hs
		343989 HS74L_HUMAN (1-840): 0: 961: 63.21		MT21A_HUMAN (1-218): 4.19e-78: 235: 100.00
+	Hs
		1360263 HS105_HUMAN (1-840): 0: 939: 62.95		MT21A_HUMAN (1-218): 4.19e-78: 235: 100.00
+	Hs
		339319 HSP74_HUMAN (1-840): 0: 996: 100.00		MET18_HUMAN (8-189): 8.87e-34: 125: 19.72
+	Hs
		761845 HSP74_HUMAN (1-840): 0: 996: 100.00		ANM1_HUMAN (57-208): 4.59e-33: 123: 16.03
+	Hs
		344009 HS74L_HUMAN (1-840): 0: 961: 63.21		ANM1_HUMAN (57-208): 4.59e-33: 123: 16.03
+	Zm
		20918 A0A1D6LZY7_MAIZE (1-832): 0: 893: 38.18		A0A1D6HPM6_MAIZE (19-214): 2.38e-56: 182: 27.40
+	Hs
		1365219 HS105_HUMAN (1-840): 0: 939: 62.95		ANM1_HUMAN (57-208): 4.59e-33: 123: 16.03
+	Sp
		150520 HSP7F_SCHPO (2-694): 6.16e-162: 490: 42.39		ANM3_SCHPO (55-194): 3.08e-35: 132: 17.93
+	Hs
		516205 HS71B_HUMAN (564-686): 7.69e-19: 93.5: 21.77		MT21A_HUMAN (1-218): 4.19e-78: 235: 100.00
+	Hs
		537605 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		MT21A_HUMAN (1-218): 4.19e-78: 235: 100.00
+	Hs
		761464 HS71L_HUMAN (564-691): 4.11e-18: 91.2: 22.48		MT21A_HUMAN (1-218): 4.19e-78: 235: 100.00
+	Hs
		537668 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		EFMT3_HUMAN (13-216): 2.14e-64: 200: 42.51
+	Hs
		761476 HS71L_HUMAN (564-691): 4.11e-18: 91.2: 22.48		EFMT3_HUMAN (13-216): 2.14e-64: 200: 42.51
+	Hs
		537323 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		MT21C_HUMAN (21-212): 7.99e-56: 180: 31.98
+	Hs
		761422 HS71L_HUMAN (564-691): 4.11e-18: 91.2: 22.48		MT21C_HUMAN (21-212): 7.99e-56: 180: 31.98
+	Hs
		537421 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		CMKMT_HUMAN (32-218): 1.69e-48: 163: 19.07
+	Hs
		537819 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		MET22_HUMAN (7-200): 4.85e-40: 143: 21.36
+	Hs
		761501 HS71L_HUMAN (564-691): 4.11e-18: 91.2: 22.48		MET22_HUMAN (7-200): 4.85e-40: 143: 21.36
+	Hs
		537786 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		ANM1_HUMAN (57-208): 4.59e-33: 123: 16.03
+	Hs
		537481 HSP7C_HUMAN (564-692): 2.49e-18: 91.6: 16.92		ETKMT_HUMAN (44-176): 4.45e-28: 108: 22.96