Protein: MT21A
Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A)

Gene: MT21A, METTL21A
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q8WXB1

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006479 - protein methylation
GO:0008276 - protein methyltransferase activity
GO:0016279 - protein-lysine N-methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

537605

HSP7C
Heat shock cognate 71 kDa protein

5

14

Small-scale

0.723

High

761786

HSP74
Heat shock 70 kDa protein 4

4

20

High-throughput

0.694

High

1315879

F200C
Protein FAM200C

4

1

High-throughput

0.688

High

347839

BAG3
BAG family molecular chaperone regulator 3

3

0

High-throughput

0.638

High

1219799

MT21C
Protein-lysine methyltransferase METTL21C

1

13

High-throughput

0.618

High

1360266

MT21D
Protein N-lysine methyltransferase METTL21D

1

5

High-throughput

0.618

High

343989

HS74L
Heat shock 70 kDa protein 4L

2

20

High-throughput

0.611

High

931025

HSP72
Heat shock-related 70 kDa protein 2

2

14

High-throughput

0.611

High

1360263

HS105
Heat shock protein 105 kDa

2

20

High-throughput

0.611

High

1360267

HPBP1
Hsp70-binding protein 1

3

1

High-throughput

0.609

High

1312641

MSRB3
Methionine-R-sulfoxide reductase B3

2

1

High-throughput

0.606

High

1360264

PFD5
Prefoldin subunit 5

2

1

High-throughput

0.606

High

1360268

ZRAN1
Ubiquitin thioesterase ZRANB1

2

3

High-throughput

0.606

High

948452

ARPC4
Actin-related protein 2/3 complex subunit 4

2

0

High-throughput

0.580

High

1348389

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.573

High

535349

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.561

High

1253067

ZN620
Zinc finger protein 620

2

4

High-throughput

0.553

High

1360269

LZTS1
Leucine zipper putative tumor suppressor 1

2

11

High-throughput

0.553

High

1360262

ATRIP
ATR-interacting protein

1

0

High-throughput

0.549

High

347212

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

1360265

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.513

High

331188

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.479

High

761464

HS71L
Heat shock 70 kDa protein 1-like

1

14

High-throughput

0.479

High

801432

HSPA9
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

1123991

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

High-throughput

0.479

High

1191450

GRDN
Girdin

1

9

High-throughput

0.479

High

1232489

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.470

High

962903

NCALD
Neurocalcin-delta

1

0

High-throughput

0.458

High

516205

HS71B
Heat shock 70 kDa protein 1B

1

14

High-throughput

0.445

High

894056

MEOX2
Homeobox protein MOX-2

1

5

High-throughput

0.439

High

106354

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

71519

MEI4
Meiosis-specific protein MEI4

2

0

High-throughput

0.316

High

1330198

ZN655
Zinc finger protein 655

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025