HitPredict

Interactor 1: BOL3 (P39724)
BolA-like protein 3 (Altered inheritance of mitochondria protein 1)
Gene: BOL3

Interactor 2: GLRX3 (Q03835)
Monothiol glutaredoxin-3
Gene: GRX3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	18719252
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	BolA~Glutaredoxin
Common GO terms	GO:0006879 - intracellular iron ion homeostasis GO:0016226 - iron-sulfur cluster assembly GO:1990229 - iron-sulfur cluster assembly complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 Sc			1 250
+	Sc
		697320 BOL3_YEAST (1-118): 3.67e-52: 161: 100.00		GLRX4_YEAST (1-249): 5.5e-66: 206: 66.27
+	Sc
		858951 BOL2_YEAST (23-112): 7.47e-30: 105: 21.11		GLRX3_YEAST (1-250): 8.59e-73: 224: 100.00
+	Sc
		697322 BOL2_YEAST (23-112): 7.47e-30: 105: 21.11		GLRX4_YEAST (1-249): 5.5e-66: 206: 66.27
+	Sp
		145312 YETB_SCHPO (39-112): 6.19e-28: 99.4: 32.43		GLRX4_SCHPO (1-245): 2.03e-64: 202: 42.45
+	Hs
		280398 BOLA3_HUMAN (20-111): 4.24e-29: 102: 33.33		GLRX3_HUMAN (8-244): 2.98e-57: 187: 37.13
+	Sc
		763749 BOL3_YEAST (1-118): 3.67e-52: 161: 100.00		GLRX5_YEAST (148-247): 1.85e-35: 125: 43.81
+	Hs
		280471 BOLA2_HUMAN (35-110): 4.2e-27: 97.5: 29.87		GLRX3_HUMAN (8-244): 2.98e-57: 187: 37.13
+	Hs
		280488 BOLA1_HUMAN (34-112): 7.02e-24: 90.5: 29.07		GLRX3_HUMAN (8-244): 2.98e-57: 187: 37.13
+	Dm
		53885 A1Z933_DROME (40-112): 1.65e-26: 95.9: 32.88		Q9VJZ6_DROME (1-246): 9.33e-52: 169: 33.33
+	Hs
		1121855 BOLA3_HUMAN (20-111): 4.24e-29: 102: 33.33		GLRX5_HUMAN (152-246): 6.13e-41: 139: 42.71
+	At
		1196707 BOLA2_ARATH (38-117): 3.49e-26: 95.2: 29.63		GRS14_ARATH (149-246): 7.63e-42: 142: 47.96
+	At
		1227407 BOLA2_ARATH (38-117): 3.49e-26: 95.2: 29.63		GRS15_ARATH (92-246): 4.12e-42: 142: 31.65
+	Dm
		53878 A1Z933_DROME (40-112): 1.65e-26: 95.9: 32.88		Q8SXQ5_DROME (151-246): 4.18e-41: 140: 43.75
+	At
		1210847 BOLA2_ARATH (38-117): 3.49e-26: 95.2: 29.63		GRS16_ARATH (104-243): 1.44e-38: 137: 30.14
+	At
		1196490 SUFE1_ARATH (30-112): 1.11e-21: 89.4: 27.55		GRS14_ARATH (149-246): 7.63e-42: 142: 47.96
+	At
		1196493 SUFE1_ARATH (30-112): 1.11e-21: 89.4: 27.55		GRS15_ARATH (92-246): 4.12e-42: 142: 31.65
+	Hs
		1197948 BOLA1_HUMAN (34-112): 7.02e-24: 90.5: 29.07		GLRX5_HUMAN (152-246): 6.13e-41: 139: 42.71
+	At
		1196492 SUFE1_ARATH (30-112): 1.11e-21: 89.4: 27.55		GRS16_ARATH (104-243): 1.44e-38: 137: 30.14
+	At
		1323450 BOLA2_ARATH (38-117): 3.49e-26: 95.2: 29.63		GRS17_ARATH (147-246): 1.1e-27: 112: 57.00
+	At
		1196496 SUFE1_ARATH (30-112): 1.11e-21: 89.4: 27.55		GRS17_ARATH (147-246): 1.1e-27: 112: 57.00