Protein: CENPC
Inner kinetochore subunit MIF2 (CENP-C homolog) (Constitutive centromere-associated network protein MIF2) (Mitotic fidelity of chromosome transmission protein 2)

Gene: CENPC, MIF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: P35201

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
GO:0005634 - nucleus
GO:0007052 - mitotic spindle organization
GO:0007059 - chromosome segregation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

763741

MTW1
Kinetochore-associated protein MTW1

6

1

Small-scale

0.941

High

763732

CENPC
Inner kinetochore subunit MIF2

4

0

Small-scale

0.844

High

763743

DSN1
Kinetochore-associated protein DSN1

16

0

Small-scale

0.726

High

763733

CENPA
Histone H3-like centromeric protein CSE4

8

0

Small-scale

0.710

High

763746

NNF1
Kinetochore-associated protein NNF1

4

0

Small-scale

0.662

High

763738

CENPN
Inner kinetochore subunit CHL4

4

0

Small-scale

0.652

High

763756

NSL1
Kinetochore-associated protein NSL1

4

0

Small-scale

0.643

High

622918

CSK22
Casein kinase II subunit alpha'

2

1

Small-scale

0.625

High

763737

CENPU
Inner kinetochore subunit AME1

3

0

Small-scale

0.613

High

763740

AURK
Aurora kinase

2

1

Small-scale

0.602

High

381058

H2B1
Histone H2B.1

2

1

Small-scale

0.584

High

381480

H2B2
Histone H2B.2

2

1

Small-scale

0.584

High

419689

H2A2
Histone H2A.2

2

1

Small-scale

0.584

High

763753

CENPO
Inner kinetochore subunit MCM21

2

0

Small-scale

0.575

High

585900

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.561

High

763754

SGO1
Shugoshin

2

0

Small-scale

0.559

High

602002

CBF1
Centromere-binding protein 1

1

0

Small-scale

0.537

High

763750

MPS1
Serine/threonine-protein kinase MPS1

1

1

High-throughput

0.536

High

763739

CSK2C
Casein kinase II subunit beta'

2

1

Small-scale

0.535

High

763744

CENPT
Inner kinetochore subunit CNN1

1

0

High-throughput

0.513

High

440927

CDC7
Cell division control protein 7

1

1

Small-scale

0.501

High

678863

CSM1
Monopolin complex subunit CSM1

1

0

Small-scale

0.480

High

739948

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

0

Small-scale

0.480

High

763735

CENPL
Inner kinetochore subunit IML3

1

0

Small-scale

0.480

High

763751

CENPP
Inner kinetochore subunit CTF19

1

0

Small-scale

0.480

High

419400

H2A1
Histone H2A.1

1

1

Small-scale

0.479

High

625085

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.460

High

647747

RFA1
Replication factor A protein 1

1

0

Small-scale

0.460

High

735371

MCM10
Minichromosome maintenance protein 10

1

0

High-throughput

0.460

High

763752

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.460

High

763755

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.460

High

763758

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.460

High

763759

NSI1
RNA polymerase I termination factor

1

0

High-throughput

0.460

High

763760

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.460

High

382018

H4
Histone H4

1

0

Small-scale

0.458

High

763747

CENPK
Inner kinetochore subunit MCM22

1

0

High-throughput

0.458

High

763748

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

Small-scale

0.458

High

763749

CENPQ
Inner kinetochore subunit OKP1

1

0

Small-scale

0.458

High

763757

PSH1
RING finger protein PSH1

1

0

Small-scale

0.458

High

763745

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.437

High

438529

UBC2
Ubiquitin-conjugating enzyme E2 2

1

0

High-throughput

0.426

High

544402

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

763742

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.426

High

763761

CENPI
Inner kinetochore subunit CTF3

1

0

High-throughput

0.426

High

553974

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.251

Low

763734

ECM13
Protein ECM13

1

0

High-throughput

0.251

Low

763736

ICS2
Increased copper sensitivity protein 2

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025