HitPredict

Interactor 1: PFD2 (P40005)
Prefoldin subunit 2 (Genes involved in microtubule biogenesis protein 4) (Gim complex subunit 4) (GimC subunit 4)
Gene: GIM4

Interactor 2: PFD3 (P48363)
Prefoldin subunit 3 (Genes involved in microtubule biogenesis protein 2) (Gim complex subunit 2) (GimC subunit 2)
Gene: PAC10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.916

Property	Details
Experiments	19536198, 9463374, 16554755, 37968396, 9878052
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Prefoldin~Prefoldin_2
Common GO terms	GO:0005737 - cytoplasm GO:0006457 - protein folding GO:0007021 - tubulin complex assembly GO:0015631 - tubulin binding GO:0016272 - prefoldin complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 111 Sc			1 199
+	Hs
		901756 PFD2_HUMAN (6-109): 4.65e-34: 116: 37.50		PFD3_HUMAN (9-194): 4.23e-74: 223: 38.30
+	Hs
		1151022 PFD2_HUMAN (6-109): 4.65e-34: 116: 37.50		Q6FH24_HUMAN (28-194): 5.02e-61: 189: 38.46
+	Dm
		1366317 PFD2_DROME (5-109): 8.96e-29: 102: 32.38		PFD3_DROME (9-185): 3.88e-66: 203: 37.43
+	Dm
		1250580 PFD2_DROME (5-109): 8.96e-29: 102: 32.38		Q8T965_DROME (9-182): 1.23e-56: 178: 19.77